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MTPN
Description
myotrophin
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
F-actin Capping Protein Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Biological Process
Regulation Of Translation
Regulation Of Cell Size
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cardiac Muscle Hypertrophy
Regulation Of Striated Muscle Tissue Development
Neuron Differentiation
Positive Regulation Of Cell Growth
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Protein Metabolic Process
Regulation Of Barbed-end Actin Filament Capping
Pathways
Drugs
Diseases
GWAS
Alcoholic chronic pancreatitis (
28754779
)
Mean platelet volume (
32888494
)
Platelet count (
27863252
)
Platelet distribution width (
27863252
32888494
)
Venous thromboembolism adjusted for sickle cell variant rs77121243-T (
28203683
)
Novel Interacting Genes
1 novel interacting genes:
ICAM1
Interacting Genes
7 interacting genes:
CAPZB
CEBPA
MAPK1
NFKB1
REL
RELA
RIPK4
Entrez ID
136319
HPRD ID
07574
Ensembl ID
ENSG00000105887
Uniprot IDs
P58546
Q69YG1
PDB IDs
3AAA
7DF7
7DSA
7DSB
Enriched GO Terms of Interacting Partners
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Response To Peptide
Response To Cytokine
Cellular Response To Tumor Necrosis Factor
Response To Tumor Necrosis Factor
NF-kappaB P50/p65 Complex
Non-canonical NF-kappaB Signal Transduction
Cellular Response To Cytokine Stimulus
Response To Nicotine
NF-kappaB Complex
Canonical NF-kappaB Signal Transduction
Cellular Response To Nicotine
Intracellular Signaling Cassette
Actinin Binding
Cytokine-mediated Signaling Pathway
Regulation Of Inflammatory Response
Cellular Response To Angiotensin
Cellular Response To Interleukin-6
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Positive Regulation Of Immune System Process
Sequence-specific DNA Binding
Positive Regulation Of Defense Response
Response To Interleukin-6
Positive Regulation Of Inflammatory Response
Response To Angiotensin
Inflammatory Response
Response To Muscle Stretch
Signal Transduction Involved In Regulation Of Gene Expression
DNA-binding Transcription Factor Activity
Transcription Regulator Complex
Immune Response-activating Cell Surface Receptor Signaling Pathway
Transcription Cis-regulatory Region Binding
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Response To DsRNA
Gland Development
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Transcription Coactivator Binding
B Cell Receptor Signaling Pathway
Response To Lipid
Regulation Of Immune System Process
Response To Lipopolysaccharide
Regulation Of Defense Response
Tumor Necrosis Factor-mediated Signaling Pathway
Response To Molecule Of Bacterial Origin
Positive Regulation Of MiRNA Metabolic Process
Regulation Of Interleukin-12 Production
Negative Regulation Of Cytokine Production
RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding
Immune Response-activating Signaling Pathway
Positive Regulation Of DNA-templated Transcription Initiation
Intracellular Signal Transduction
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