POC5

Description		POC5 centriolar protein
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytoskeleton Photoreceptor Connecting Cilium
	Molecular Function	Protein Binding
	Biological Process	Eye Photoreceptor Cell Development Centriole Elongation Negative Regulation Of Centriole Elongation
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 26961502 29615537 29273807 28892062 28552196 28448500 25673413) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Diastolic blood pressure ( 27841878 30578418 28135244) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Metabolic syndrome ( 31589552) Pulse pressure ( 30578418) Total cholesterol levels ( 29615537) Type 2 diabetes ( 29632382 30054458 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382) Weight ( 28552196)
Interacting Genes		5 interacting genes: CALM1 CALM2 CALM3 CETN1 FAM161A
Entrez ID		134359
HPRD ID		08188
Ensembl ID		ENSG00000152359
Uniprot IDs		Q8NA72
PDB IDs
Enriched GO Terms of Interacting Partners?		Spindle Microtubule Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Titin Binding Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Calyx Of Held Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Transporter Activity Calcium Channel Complex Spindle Pole Calcineurin-mediated Signaling Presynaptic Cytosol Myelin Sheath Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Centrosome Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of Calcium Ion Transmembrane Transport Presynaptic Endocytosis Substantia Nigra Development Calcium Channel Regulator Activity Sperm Midpiece Negative Regulation Of Calcium Ion Transport G2/M Transition Of Mitotic Cell Cycle Long-term Synaptic Potentiation Sarcomere Cell Cycle G2/M Phase Transition Neural Nucleus Development Negative Regulation Of Cation Transmembrane Transport Protein Serine/threonine Kinase Activator Activity Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Monoatomic Ion Transmembrane Transport Voltage-gated Potassium Channel Complex Calcium-dependent Protein Binding Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cardiac Muscle Contraction Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Cytokinesis Positive Regulation Of Sequestering Of Calcium Ion Vesicle-mediated Transport In Synapse Regulation Of Calcium-mediated Signaling
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