PPM1M

Description		protein phosphatase, Mg2+/Mn2+ dependent 1M
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity [pyruvate Dehydrogenase (acetyl-transferring)]-phosphatase Activity Hydrolase Activity Manganese Ion Binding Metal Ion Binding
	Biological Process	Protein Dephosphorylation
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Schizophrenia ( 23974872)
Interacting Genes		2 interacting genes: AATK ERBB3
Entrez ID		132160
HPRD ID		12350
Ensembl ID		ENSG00000164088
Uniprot IDs		Q96MI6
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuron Apoptotic Process Protein Tyrosine Kinase Activity Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Neuregulin Receptor Activity ErbB-3 Class Receptor Binding Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Schwann Cell Differentiation Protein Kinase Activity ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Negative Regulation Of Motor Neuron Apoptotic Process Kinase Activity Endocardial Cushion Development Regulation Of Motor Neuron Apoptotic Process Motor Neuron Apoptotic Process Positive Regulation Of Striated Muscle Tissue Development Apoptotic Process Schwann Cell Development ERBB2 Signaling Pathway Protein Tyrosine Kinase Activator Activity Positive Regulation Of Calcineurin-NFAT Signaling Cascade Cell Death Peripheral Nervous System Development Programmed Cell Death Cranial Nerve Development Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Striated Muscle Tissue Development Growth Factor Binding Regulation Of Muscle Organ Development Nerve Development ATP Binding Positive Regulation Of Calcium-mediated Signaling Animal Organ Development Mesenchyme Development Glial Cell Development Epidermal Growth Factor Receptor Signaling Pathway Basal Plasma Membrane Lateral Plasma Membrane Wound Healing ERBB Signaling Pathway Nucleotide Binding Transferase Activity Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Calcium-mediated Signaling Myelination Axon Ensheathment
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