COL16A1

Description		collagen type XVI alpha 1 chain
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Collagen Type XVI Trimer Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function	Integrin Binding Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Cell Adhesion Integrin-mediated Signaling Pathway Female Pregnancy Integrin Activation Cell Adhesion Mediated By Integrin Positive Regulation Of Focal Adhesion Assembly Cellular Response To Amino Acid Stimulus
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Integrin cell surface interactions Collagen chain trimerization
Drugs
Diseases
GWAS		Asthma ( 31959851 32296059) Body mass index ( 25673413 26426971) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Severe aortic features in Marfan syndrome ( 30087447)
Novel Interacting Genes		1 novel interacting genes: ZEB2
Interacting Genes
Entrez ID		1307
HPRD ID		00381
Ensembl ID		ENSG00000084636
Uniprot IDs		Q07092
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Melanosome Organization Regulation Of Myofibroblast Contraction Mammillary Axonal Complex Development Regulation Of Myofibroblast Cell Apoptotic Process Positive Regulation Of Lens Fiber Cell Differentiation Positive Regulation Of Myofibroblast Contraction Phosphatase Regulator Activity Regulation Of Melanocyte Differentiation Corticospinal Tract Morphogenesis Melanocyte Migration Myofibroblast Differentiation Corpus Callosum Morphogenesis Positive Regulation Of Pigment Cell Differentiation Positive Regulation Of Melanocyte Differentiation Fibroblast Activation Positive Regulation Of Developmental Pigmentation Regulation Of Lens Fiber Cell Differentiation Regulation Of Blood-brain Barrier Permeability Positive Regulation Of Melanin Biosynthetic Process Response To Oxygen-glucose Deprivation Regulation Of Melanin Biosynthetic Process Regulation Of Developmental Pigmentation Cell Proliferation In Forebrain Negative Regulation Of Fibroblast Migration Developmental Pigmentation Collateral Sprouting Astrocyte Activation Contractile Actin Filament Bundle Assembly Stress Fiber Assembly Central Nervous System Projection Neuron Axonogenesis R-SMAD Binding Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Central Nervous System Neuron Axonogenesis Epithelial Cell Migration Endothelial Cell Proliferation Regulation Of Fibroblast Migration Pyroptotic Inflammatory Response Somitogenesis Regulation Of Vascular Permeability Pigmentation Segmentation Neural Crest Cell Migration Mesenchymal Cell Migration Actin Filament Bundle Assembly Positive Regulation Of Epithelial Cell Differentiation Actin Filament Bundle Organization Hippocampus Development Positive Regulation Of Axonogenesis Endothelial Cell Migration Neural Tube Closure
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