TMEM18

Description		transmembrane protein 18
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Membrane Nuclear Membrane
	Molecular Function	DNA Binding Protein Binding
	Biological Process	Cell Migration Eating Behavior Energy Homeostasis
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) BMI in smokers ( 28443625) Body fat percentage ( 26833246) Body mass index ( 28892062 26426971 25673413 19079261 20935630 31453325 29381148 24861553 28448500 24064335 23669352 26961502 19079260 23563607 28552196) Body mass index (adult) ( 28430825) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Body mass index variance ( 31453325) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Body size at age 10 ( 32376654) Breast size ( 27182965) C-reactive protein levels ( 30388399) Caffeine consumption from coffee ( 33287642) Childhood body mass index ( 26604143 33045005) Coffee consumption ( 31046077) Fasting insulin ( 34059833) Hand grip strength ( 29691431) Heel bone mineral density ( 28869591 30598549) Heschl's gyrus morphology ( 25130324) Hip circumference ( 31453325 25673412) Hip circumference variance ( 31453325) Menarche (age at onset) ( 21102462 27182965 25231870) Metabolic syndrome ( 31589552) Obese vs. thin ( 30677029) Obesity ( 23563607) Obesity (early onset extreme) ( 23563609 20421936) Obesity (extreme) ( 30677029) Obesity-related traits ( 23251661) Parental lifespan ( 30642433) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Refractive error ( 32231278) Response to fenofibrate (adiponectin levels) ( 23149075) Response to protease inhibitor treatment in hepatitis c (peak serum total bilirubin levels) ( 24503447) Serum uric acid levels ( 30993211) Smoking initiation ( 33082346 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Type 2 diabetes ( 30297969 30054458 30718926 28869590 32499647 24509480) Urate levels ( 31578528) Uric acid levels ( 22229870) Waist circumference ( 31453325 28552196 25673412) Waist circumference variance ( 31453325) Weight ( 28552196 19079260)
Interacting Genes		2 interacting genes: REEP4 RETREG3
Entrez ID		129787
HPRD ID		15529
Ensembl ID		ENSG00000151353
Uniprot IDs		B5MBX8 Q96B42
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Organization Endoplasmic Reticulum-autophagosome Adaptor Activity Mitotic Nuclear Membrane Reassembly Substrate Localization To Autophagosome Nuclear Membrane Reassembly Nuclear Envelope Organization Reticulophagy Endoplasmic Reticulum Membrane Collagen Catabolic Process Nuclear Membrane Organization Membrane Assembly Cytoplasmic Microtubule Endoplasmic Reticulum Collagen Metabolic Process
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