XIRP2

Description		xin actin binding repeat containing 2
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GO Annotations	Cellular Component	Stress Fiber Cell-cell Junction Focal Adhesion Z Disc Cell Junction Anchoring Junction
	Molecular Function	Actin Binding Protein Binding Actin Filament Binding Alpha-actinin Binding
	Biological Process	Ventricular Septum Development Actin Filament Organization Actin Cytoskeleton Organization Cell-cell Junction Organization Cardiac Muscle Tissue Morphogenesis Regulation Of Actin Filament Organization Positive Regulation Of Protein Localization
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Atopic dermatitis ( 25865352) Diabetic peripheral neuropathy in type 2 diabetes ( 31127053) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels in HIV infection ( 33109212) Plasma renin activity levels ( 29650764)
Interacting Genes		6 interacting genes: DYSF FLNC LRRK2 NEB NEBL VASP
Entrez ID		129446
HPRD ID		10267
Ensembl ID		ENSG00000163092
Uniprot IDs		A4UGR9
PDB IDs		4F14
Enriched GO Terms of Interacting Partners?		Actin Binding Cardiac Muscle Thin Filament Assembly Z Disc Actin Filament Binding Actin Filament Organization Structural Constituent Of Muscle Extracellular Exosome Cytoskeletal Protein Binding Monocyte Activation Involved In Immune Response Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Regulation Of Neurotransmitter Secretion Sarcolemma Cytoskeleton Supramolecular Fiber Organization Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Beta-catenin Destruction Complex Binding Regulation Of Actin Filament Length Synaptic Vesicle Membrane Positive Regulation Of Protein Autoubiquitination Response To Curcumin Somatic Muscle Development Cytoplasmic Side Of Mitochondrial Outer Membrane Positive Regulation Of Dopamine Receptor Signaling Pathway Multivesicular Body, Internal Vesicle Regulation Of CAMKK-AMPK Signaling Cascade Regulation Of Branching Morphogenesis Of A Nerve Regulation Of Synaptic Vesicle Transport Regulation Of Protein Autoubiquitination Positive Regulation Of Synaptic Vesicle Endocytosis Negative Regulation Of Protein Targeting To Mitochondrion Regulation Of Kidney Size Tangential Migration From The Subventricular Zone To The Olfactory Bulb Positive Regulation Of Synaptic Vesicle Recycling Cellular Response To Dopamine Intracellular Distribution Of Mitochondria Regulation Of Retrograde Transport, Endosome To Golgi Postsynapse Positive Regulation Of Microglial Cell Activation Protein Localization To Endoplasmic Reticulum Exit Site Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Response To Dopamine Regulation Of Cellular Component Size JUN Kinase Kinase Kinase Activity Regulation Of Neuron Maturation
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