DUSP15

Description		dual specificity phosphatase 15
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Hydrolase Activity Phosphatase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Signal Transduction Dephosphorylation Regulation Of Oligodendrocyte Differentiation Positive Regulation Of ERK1 And ERK2 Cascade
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)
Novel Interacting Genes		1 novel interacting genes: POFUT1
Interacting Genes		2 interacting genes: IGF1R PTK7
Entrez ID		128853
HPRD ID		13252
Ensembl ID		ENSG00000149599
Uniprot IDs		Q9H1R2
PDB IDs		1YZ4
Enriched GO Terms of Interacting Partners?		Insulin-like Growth Factor Receptor Activity Protein Kinase Complex Insulin Receptor Complex Alphav-beta3 Integrin-IGF-1-IGF1R Complex Insulin Binding Insulin Receptor Activity Heart Development Protein O-linked Glycosylation Via Fucose Peptide-O-fucosyltransferase Activity Axon Peptidyl-tyrosine Autophosphorylation Insulin-like Growth Factor Binding Protein Kinase Activity Cell Surface Receptor Signaling Pathway Insulin-like Growth Factor I Binding Dendritic Spine Maintenance Insulin Receptor Substrate Binding Protein Transporter Activity Lung-associated Mesenchyme Development Axon Guidance Receptor Activity Convergent Extension Fucose Metabolic Process Phosphatidylinositol 3-kinase Binding Establishment Of Epithelial Cell Apical/basal Polarity Axis Elongation Transcytosis Insulin Receptor Binding Establishment Of Planar Polarity Establishment Of Apical/basal Cell Polarity Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Polarized Epithelial Cell Differentiation Amyloid-beta Clearance Coronary Vasculature Development Cochlea Morphogenesis Establishment Of Epithelial Cell Polarity Regulation Of Signal Transduction Dendritic Spine Organization Insulin-like Growth Factor Receptor Signaling Pathway Ventricular Septum Development Positive Regulation Of Protein-containing Complex Disassembly Anatomical Structure Formation Involved In Morphogenesis Regulation Of Cell Communication Transmembrane Receptor Protein Tyrosine Kinase Activity Neuron Projection Organization Cellular Response To Amyloid-beta Plasma Membrane Bounded Cell Projection Organization Postsynapse Organization Peptidyl-tyrosine Phosphorylation Cellular Response To Oxygen-containing Compound
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