TYW3

Description		tRNA-yW synthesizing protein 3 homolog
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Binding Methyltransferase Activity TRNA Methyltransferase Activity Transferase Activity
	Biological Process	TRNA Processing TRNA Methylation Wybutosine Biosynthetic Process Methylation
Pathways		Synthesis of wybutosine at G37 of tRNA(Phe)
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Menarche (age at onset) ( 25231870) Resistin levels ( 22843503) Self-reported tiredness ( 28194004) Visceral fat ( 22589738)
Interacting Genes		2 interacting genes: DDIT4L PICK1
Entrez ID		127253
HPRD ID		14036
Ensembl ID		ENSG00000162623
Uniprot IDs		Q6IPR3 Q96GE7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Membrane Curvature Sensor Activity Negative Regulation Of Actin Nucleation Neuronal Ion Channel Clustering Dendritic Spine Maintenance Arp2/3 Complex Binding Long-term Synaptic Depression Cellular Response To Glucose Starvation Receptor Clustering Positive Regulation Of Receptor Internalization Neuron Projection Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Monoamine Transport Protein Kinase C Binding Dendritic Spine Organization Postsynapse Organization Negative Regulation Of Synaptic Transmission Regulation Of Actin Nucleation Positive Regulation Of Receptor-mediated Endocytosis Endocytic Vesicle Membrane Cellular Component Maintenance Regulation Of Receptor Internalization G Protein-coupled Receptor Binding Glial Cell Development Negative Regulation Of Cell Communication Negative Regulation Of Signaling
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