FBXO27

Description		F-box protein 27
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Glycoprotein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process ERAD Pathway
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: SKP1 STUB1
Entrez ID		126433
HPRD ID		16440
Ensembl ID		ENSG00000161243
Uniprot IDs		A0A384MR61 Q8NI29
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Monoubiquitination Positive Regulation Of Chaperone-mediated Protein Complex Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Programmed Cell Death Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process F-box Domain Binding Proteasomal Protein Catabolic Process Ubiquitin Ligase Activator Activity Protein Catabolic Process Protein Ubiquitination Positive Regulation Of Apoptotic Process Cul7-RING Ubiquitin Ligase Complex Ubiquitin Ligase Complex Scaffold Activity Modification-dependent Protein Catabolic Process Chaperone-mediated Autophagy Nuclear Inclusion Body Regulation Of Glucocorticoid Metabolic Process Regulation Of Vascular Associated Smooth Muscle Contraction Negative Regulation Of Vascular Associated Smooth Muscle Contraction Cellular Response To Misfolded Protein TPR Domain Binding Ubiquitin Conjugating Enzyme Complex Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Negative Regulation Of Smooth Muscle Contraction Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Vasoconstriction Response To Misfolded Protein Positive Regulation Of ERAD Pathway Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Ubiquitin-ubiquitin Ligase Activity Negative Regulation Of Smooth Muscle Cell Apoptotic Process Positive Regulation Of Smooth Muscle Cell Apoptotic Process Misfolded Protein Binding Post-translational Protein Modification Negative Regulation Of Muscle Contraction Positive Regulation Of Epithelial Cell Apoptotic Process Maintenance Of Protein Location In Nucleus PcG Protein Complex Cullin Family Protein Binding Molecular Function Activator Activity Positive Regulation Of Mitophagy Positive Regulation Of Autophagy Of Mitochondrion Regulation Of ERAD Pathway ERBB2 Signaling Pathway R-SMAD Binding Cellular Response To Topologically Incorrect Protein Macromolecule Catabolic Process Protein Folding Chaperone Complex
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