KRT222

Description		keratin 222
Image		No pdb structure
GO Annotations	Cellular Component	Intermediate Filament
	Molecular Function	Structural Molecule Activity Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474 31959851) Asthma or allergic disease (pleiotropy) ( 29785011) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		4 interacting genes: DSCAM HSPA6 ITSN1 KDM1A
Entrez ID		125113
HPRD ID		11354
Ensembl ID		ENSG00000213424
Uniprot IDs		Q8N1A0
PDB IDs
Enriched GO Terms of Interacting Partners?		Netrin-activated Signaling Pathway Post-embryonic Retina Morphogenesis In Camera-type Eye Positive Regulation Of Cellular Component Organization Positive Regulation Of Axon Extension Involved In Axon Guidance Netrin Receptor Binding Positive Regulation Of Neurogenesis Positive Regulation Of Nervous System Development Positive Regulation Of Developmental Process Cellular Heat Acclimation Postsynaptic Endocytic Zone Positive Regulation Of Caveolin-mediated Endocytosis Clathrin-dependent Synaptic Vesicle Endocytosis Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Growth Hormone Secretion Regulation Of Modification Of Postsynaptic Actin Cytoskeleton Response To Fungicide MRF Binding Histone H3K4 Demethylase Activity Guanine Metabolic Process Protein Demethylase Activity Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Cell Development Regulation Of Axon Extension Involved In Axon Guidance Dendrite Self-avoidance Camera-type Eye Photoreceptor Cell Differentiation Regulation Of Neuron Projection Development Dendritic Spine Development Neuronal Cell Body Regulation Of Neurogenesis Regulation Of Nervous System Development Positive Regulation Of Cell Projection Organization Enzyme Binding Apical Dendrite Regulation Of Growth Hormone Secretion Regulation Of Modification Of Postsynaptic Structure Postsynaptic Actin Cytoskeleton Histone H3K9 Demethylase Activity Positive Regulation Of Cell Size Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator DNA Repair Complex Eye Photoreceptor Cell Differentiation Photoreceptor Cell Differentiation Intracellular Vesicle Proline-rich Region Binding Regulation Of Modification Of Synaptic Structure Purine Nucleobase Metabolic Process Histone Demethylase Activity
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