CCR7

Gene Name		chemokine (C-C motif) receptor 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Plasma Membrane External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	G-protein Coupled Receptor Activity C-C Chemokine Receptor Activity Chemokine (C-C Motif) Ligand 19 Binding Chemokine (C-C Motif) Ligand 21 Binding C-C Motif Chemokine 19 Receptor Activity C-C Motif Chemokine 21 Receptor Activity
	Biological Process	Establishment Of T Cell Polarity Positive Regulation Of Cell-matrix Adhesion Dendritic Cell Chemotaxis Myeloid Dendritic Cell Chemotaxis Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Positive Regulation Of Hypersensitivity Positive Regulation Of Humoral Immune Response Inflammatory Response Immune Response G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Ruffle Organization Response To Lipopolysaccharide Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-12 Production Activation Of Rho GTPase Activity Response To Prostaglandin E Chemokine (C-C Motif) Ligand 19 Signaling Pathway Chemokine (C-C Motif) Ligand 21 Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Phosphatidylinositol 3-kinase Activity Negative Thymic T Cell Selection Positive Regulation Of Cell Adhesion Positive Regulation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Regulation Of Interleukin-1 Beta Secretion Positive Regulation Of T Cell Receptor Signaling Pathway Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Filopodium Assembly Positive Regulation Of Protein Kinase B Signaling Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Cytokine Stimulus Response To Nitric Oxide Interleukin-12 Secretion Positive Regulation Of Neutrophil Chemotaxis Lymphocyte Migration Into Lymph Node Mature Conventional Dendritic Cell Differentiation Negative Regulation Of Leukocyte Apoptotic Process Positive Regulation Of Cell Motility Positive Regulation Of Dendritic Cell Chemotaxis Positive Regulation Of Immunological Synapse Formation Positive Regulation Of T Cell Costimulation Positive Regulation Of Glycoprotein Biosynthetic Process Involved In Immunological Synapse Formation Regulation Of Dendritic Cell Dendrite Assembly
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: CCL19 CCL21 CCR10
Entrez ID		1236
HPRD ID		02588
Ensembl ID		ENSG00000126353
Uniprot IDs		A0N0Q0 P32248
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Dendritic Cell Dendrite Assembly Establishment Of T Cell Polarity Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Cytosolic Calcium Ion Homeostasis Dendritic Cell Chemotaxis Immunological Synapse Formation Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Glycoprotein Metabolic Process Response To Prostaglandin E Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Positive Regulation Of Neutrophil Chemotaxis Dendritic Cell Migration Positive Regulation Of Granulocyte Chemotaxis Positive Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Glycoprotein Biosynthetic Process Regulation Of Neutrophil Chemotaxis Regulation Of Neutrophil Migration Cellular Metal Ion Homeostasis Inflammatory Response Cellular Cation Homeostasis Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Granulocyte Chemotaxis Cellular Ion Homeostasis Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Sequestering Of Calcium Ion Metal Ion Homeostasis Leukocyte Activation Calcium Ion Transport Into Cytosol Cytosolic Calcium Ion Transport Cellular Chemical Homeostasis Regulation Of Phosphatidylinositol 3-kinase Activity Ion Homeostasis Negative Regulation Of Leukocyte Apoptotic Process Chemotaxis Regulation Of Lipid Kinase Activity Cell-cell Recognition Positive Regulation Of Leukocyte Chemotaxis Cell Activation Cellular Homeostasis Response To Fatty Acid T Cell Costimulation Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Leukocyte Migration Chemical Homeostasis Leukocyte Chemotaxis Positive Regulation Of Endocytosis Positive Regulation Of Chemotaxis Establishment Of Cell Polarity
Tagcloud ?		capture ccr1 ccr2 ccr5 cd40 chemokine chemokines cxcr1 cxcr4 dc dendritic ebi1 elc immature inflamed insight lost lymphoid marginally maturation mature maturing migrate nodes organs phases respective responded responsiveness