ALKBH2

Description		alkB homolog 2, alpha-ketoglutarate dependent dioxygenase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus
	Molecular Function	RDNA Binding Protein Binding Ferrous Iron Binding Oxidoreductase Activity 2-oxoglutarate-dependent Dioxygenase Activity Broad Specificity Oxidative DNA Demethylase Activity Metal Ion Binding Dioxygenase Activity Cytosine C-5 DNA Demethylase Activity
	Biological Process	DNA Repair DNA Alkylation Repair DNA Damage Response
Pathways		ALKBH2 mediated reversal of alkylation damage
Drugs		Ascorbic acid
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: NDFIP2
Interacting Genes		1 interacting genes: GOLGA2
Entrez ID		121642
HPRD ID		14712
Ensembl ID		ENSG00000189046
Uniprot IDs		Q6NS38
PDB IDs		3BTX 3BTY 3BTZ 3BU0 3BUC 3H8O 3H8R 3H8X 3RZG 3RZH 3RZJ 3RZK 3RZL 3RZM 3S57 3S5A 4MG2 4MGT
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Glycosylation Golgi Cis Cisterna Regulation Of Protein Glycosylation Positive Regulation Of Protein Modification Process Golgi Ribbon Formation Regulation Of Protein Modification Process Golgi Membrane Asymmetric Cell Division Importin-alpha Family Protein Binding Golgi Disassembly Meiotic Spindle Assembly Positive Regulation Of Protein Metabolic Process Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Glycoprotein Biosynthetic Process Meiotic Spindle Organization WW Domain Binding Negative Regulation Of Protein Binding Microtubule Nucleation Negative Regulation Of Transporter Activity Multivesicular Body Membrane Regulation Of Glycoprotein Biosynthetic Process Syntaxin Binding COPII-coated ER To Golgi Transport Vesicle Regulation Of Protein Binding Centrosome Cycle Cis-Golgi Network Golgi Apparatus Intracellular Transport Mitotic Spindle Assembly Protein Homotetramerization Golgi Cisterna Membrane Cellular Localization Establishment Of Localization In Cell Regulation Of Protein Metabolic Process Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Organelle Disassembly Microtubule Organizing Center Organization Mitotic Spindle Organization Spindle Assembly Protein Tetramerization Negative Regulation Of Autophagy Positive Regulation Of Protein Ubiquitination Golgi Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Negative Regulation Of Protein Transport Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of Post-translational Protein Modification Mitotic Spindle Negative Regulation Of Establishment Of Protein Localization
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