FAT3

Description		FAT atypical cadherin 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Adherens Junction Membrane Dendrite Neuron Projection
	Molecular Function	Calcium Ion Binding
	Biological Process	Neuron Migration Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Animal Organ Morphogenesis Retina Layer Formation Dendrite Development Cell-cell Adhesion Mediated By Cadherin Anatomical Structure Formation Involved In Morphogenesis Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Plasma Membrane Bounded Cell Projection Organization Interneuron Migration Negative Regulation Of Dendrite Development
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Brain morphology (MOSTest) ( 32665545) Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Colorectal adenoma (advanced) ( 29228715) Dental caries (decayed and filled deciduous teeth) ( 31533690) Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690) Glucose homeostasis traits ( 25524916) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Heel bone mineral density ( 30598549) Height ( 28552196) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Late-onset Alzheimer's disease ( 27770636) Lateral thalamic nuclei volume ( 34006833) Optic cup area ( 31798171) Osteoarthritis of the hand ( 28855172) Periodontitis (stage III/IV grade C) ( 33745150) Photic sneeze reflex ( 27182965) Proportion of activated microglia (midfrontal cortex) ( 30679421) Pulse pressure ( 30578418) Refractive error ( 32231278) Retinal detachment ( 31816047 32352494) Retinal detachment or retinal break ( 31816047) Retinal detachment with retinal break ( 31816047) Subcortical brain region volumes ( 25607358)
Interacting Genes		1 interacting genes: USP7
Entrez ID		120114
HPRD ID		18543
Ensembl ID		ENSG00000165323
Uniprot IDs		Q8TDW7
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Retrograde Transport, Endosome To Golgi Monoubiquitinated Protein Deubiquitination DNA Alkylation Repair Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Regulation Of Telomere Capping Negative Regulation Of Gluconeogenesis K48-linked Deubiquitinase Activity Deubiquitinase Activity Nucleotide-excision Repair Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of TORC1 Signaling Regulation Of Gluconeogenesis Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process TORC1 Signaling Cysteine-type Endopeptidase Activity Negative Regulation Of Autophagy Negative Regulation Of Small Molecule Metabolic Process P53 Binding Cysteine-type Deubiquitinase Activity Autophagosome Organization Protein Deubiquitination Protein Modification By Small Protein Removal Autophagosome Assembly Regulation Of TORC1 Signaling Regulation Of Circadian Rhythm Negative Regulation Of TOR Signaling TOR Signaling Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Protein Catabolic Process Regulation Of Telomere Maintenance Regulation Of Glucose Metabolic Process PML Body Cysteine-type Peptidase Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Regulation Of TOR Signaling Vacuole Organization Negative Regulation Of Gene Expression, Epigenetic Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Autophagy Regulation Of DNA-binding Transcription Factor Activity Regulation Of Proteasomal Protein Catabolic Process Protein Stabilization Regulation Of Chromosome Organization
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