CLCNKB

Description		chloride voltage-gated channel Kb
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Chloride Channel Complex
	Molecular Function	Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding Chloride Transmembrane Transporter Activity Metal Ion Binding
	Biological Process	Monoatomic Ion Transport Chloride Transport Transepithelial Chloride Transport Monoatomic Ion Transmembrane Transport Transmembrane Transport Renal Absorption Renal Sodium Ion Absorption Chloride Transmembrane Transport
Pathways		Stimuli-sensing channels
Drugs
Diseases		Bartter syndrome
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Red blood cell count ( 27863252 32888494)
Interacting Genes		1 interacting genes: CFTR
Entrez ID		1188
HPRD ID		03607
Ensembl ID		ENSG00000184908
Uniprot IDs		A8K8H0 P51801
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle Docking Cholesterol Transport Clathrin-coated Endocytic Vesicle Membrane Odontogenesis Of Dentin-containing Tooth Chloride Channel Activity Multicellular Organismal-level Chemical Homeostasis Regulation Of Cellular PH Regulation Of Transmembrane Transporter Activity Membrane Docking Positive Regulation Of Exocytosis
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