C10orf90

Description		chromosome 10 open reading frame 90
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Actin Cytoskeleton
	Molecular Function	Transferase Activity Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Protein Ubiquitination Regulation Of Centriole Replication Protein Stabilization
Pathways
Drugs
Diseases
GWAS		Age-related hearing impairment ( 34108613) Airway wall thickness ( 25517131) Early spontaneous preterm birth ( 31194736) Gestational age at birth (child effect) ( 31194736) Metabolite levels (MHPG) ( 23319000) Resistance to Mycobacterium tuberculosis infection ( 33661925) Response to TNF inhibitor in rheumatoid arthritis (change in disease activity score) ( 30166627) Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627) Sitting height ratio ( 25865494)
Novel Interacting Genes		1 novel interacting genes: DOCK1
Interacting Genes		3 interacting genes: GSK3B MTNR1A TP53
Entrez ID		118611
HPRD ID		16587
Ensembl ID		ENSG00000154493
Uniprot IDs		Q96M02 S4R3N7
PDB IDs
Enriched GO Terms of Interacting Partners?		ER Overload Response Circadian Rhythm Positive Regulation Of Mitochondrial Membrane Permeability Rhythmic Process Positive Regulation Of Membrane Permeability ER-nucleus Signaling Pathway Regulation Of Mitochondrial Membrane Permeability P53 Binding Regulation Of Membrane Permeability Positive Regulation Of Neuron Apoptotic Process Membrane Organization Regulation Of Circadian Rhythm Mitochondrial Membrane Organization Regulation Of Mitochondrion Organization Regulation Of Microtubule Anchoring At Centrosome Protease Binding Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Positive Regulation Of Cell-substrate Adhesion Intracellular Signaling Cassette Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Proteolysis Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Generation Of Precursor Metabolites And Energy Viral Process Oligodendrocyte Apoptotic Process Negative Regulation Of Pentose-phosphate Shunt Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of Catalytic Activity Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Oxidative Stress-induced Premature Senescence Glucose Catabolic Process To Lactate Via Pyruvate Germ Cell Nucleus Cellular Response To Actinomycin D RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Cell-substrate Adhesion Negative Regulation Of TORC2 Signaling Negative Regulation Of Dopaminergic Neuron Differentiation Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Protein-containing Complex Assembly Melatonin Receptor Activity Positive Regulation Of Thymocyte Apoptotic Process Response To Actinomycin D T Cell Proliferation Involved In Immune Response Postsynapse Response To Endoplasmic Reticulum Stress
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