IP6K3

Description		inositol hexakisphosphate kinase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding Inositol-1,3,4,5,6-pentakisphosphate Kinase Activity Inositol Hexakisphosphate Kinase Activity Diphosphoinositol Pentakisphosphate Kinase Activity Inositol Hexakisphosphate 6-kinase Activity Inositol Hexakisphosphate 5-kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Inositol 5-diphosphate Pentakisphosphate 5-kinase Activity Diphosphoinositol Tetrakisphosphate Kinase Activity
	Biological Process	Protein Phosphorylation Inositol Phosphate Biosynthetic Process Locomotion Inositol Phosphate Metabolic Process Phosphatidylinositol Metabolic Process Phosphatidylinositol Phosphate Biosynthetic Process Organophosphate Biosynthetic Process
Pathways		Synthesis of pyrophosphates in the cytosol
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Asthma and attention deficit hyperactivity disorder ( 31619474) Body mass index ( 26426971) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Crohn's disease ( 23850713) HDL cholesterol levels ( 32203549) Height ( 28552196) Hodgkin's lymphoma ( 30194254) Multiple sclerosis and waist-to-hip-ratio (pleiotropy) ( 26920376) Phosphorus levels ( 29403010) Platelet count ( 32888494) Plateletcrit ( 27863252 32888494) Regular attendance at a gym or sports club ( 29970889)
Interacting Genes		14 interacting genes: FHL5 KRTAP10-8 LNX1 MED4 MEOX2 NIF3L1 NOTO POLR2E TRAF2 TRAF3 TRIM27 TRIP6 ZNF655 ZRANB1
Entrez ID		117283
HPRD ID		07381
Ensembl ID		ENSG00000161896
Uniprot IDs		A8K1M0 Q5TAQ4 Q96PC2
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin-protein Transferase Activity Thioesterase Binding CD40 Receptor Complex Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Ubiquitin Protein Ligase Activity Nuclear Thyroid Hormone Receptor Binding Tumor Necrosis Factor Receptor Binding Regulation Of RNA Metabolic Process Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process TORC2 Complex Disassembly Embryonic Pattern Specification Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Transcription By RNA Polymerase II Transcription Coactivator Activity Protein K63-linked Ubiquitination Identical Protein Binding TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding
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