GRIN3B

Gene Name		glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	N-methyl-D-aspartate Selective Glutamate Receptor Complex Cell Junction Dendrite Neuronal Cell Body Postsynaptic Membrane
	Molecular Function	N-methyl-D-aspartate Selective Glutamate Receptor Activity Extracellular-glutamate-gated Ion Channel Activity Cation Channel Activity Calcium Channel Activity Glycine Binding Neurotransmitter Receptor Activity Neurotransmitter Binding
	Biological Process	Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Protein Insertion Into Membrane Regulation Of Calcium Ion Transport Calcium Ion Transmembrane Transport
Pathways
Drugs		L-Glutamic Acid Glycine Halothane Orphenadrine Tenocyclidine
Diseases
GWAS		Alzheimer's disease (late onset) ( 23571587)
Protein-protein Interactions		2 interactors: DLG4 GRIN2A
Entrez ID		116444
HPRD ID		09444
Ensembl ID		ENSG00000116032
Uniprot IDs		O60391
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Membrane Depolarization Neuromuscular Process Learning Regulation Of Synaptic Plasticity Learning Or Memory Regulation Of Membrane Potential Cognition Regulation Of Synaptic Transmission Directional Locomotion Single-organism Behavior Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Maintenance Of Apical/basal Cell Polarity Receptor Localization To Synapse Synaptic Transmission Behavior Negative Regulation Of Receptor Internalization Locomotory Exploration Behavior Dendritic Spine Morphogenesis Maintenance Of Cell Polarity Synaptic Vesicle Maturation Vocalization Behavior Serotonin Metabolic Process Sleep Dendritic Spine Development Protein Localization To Synapse Cell-cell Signaling Negative Regulation Of Receptor-mediated Endocytosis Dendritic Spine Organization Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Cortical Actin Cytoskeleton Organization Exploration Behavior Postsynaptic Membrane Organization Regulation Of Sensory Perception Of Pain Establishment Or Maintenance Of Apical/basal Cell Polarity Startle Response Dopamine Metabolic Process Cortical Cytoskeleton Organization Neurological System Process Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Receptor Internalization Positive Regulation Of Excitatory Postsynaptic Membrane Potential Locomotion Golgi To Plasma Membrane Transport Response To Amphetamine Synaptic Vesicle Endocytosis Synaptic Vesicle Recycling Social Behavior
Tagcloud ?		asd autism compensation counteract de disability excitatory exploring grin1 grin2a grin2c grin2d hypofunction imbalance implicate instrumental intellectual neurodevelopment neurodevelopmental neurotransmission nmdars novo scz sequenced sporadic truncating