SLC22A12

Gene Name		solute carrier family 22 (organic anion/urate transporter), member 12
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Brush Border Membrane Extracellular Vesicular Exosome
	Molecular Function	Urate Transmembrane Transporter Activity PDZ Domain Binding
	Biological Process	Urate Transport Organic Acid Transport Cellular Homeostasis Response To Drug Urate Metabolic Process Transmembrane Transport
Pathways		Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Organic anion transport Organic cation/anion/zwitterion transport SLC-mediated transmembrane transport
Drugs
Diseases
GWAS		Renal function-related traits (urea) ( 22797727) Urate levels ( 21768215 20139978 23263486) Uric acid levels ( 19503597)
Protein-protein Interactions		1 interactors: PDZK1
Entrez ID		116085
HPRD ID		06160
Ensembl ID		ENSG00000197891
Uniprot IDs		B3KP53 B5ME56 G3XAN7 Q96S37
PDB IDs
Enriched GO Terms of Interacting Partners?		Carnitine Transport Quaternary Ammonium Group Transport Positive Regulation Of Protein Targeting To Membrane Drug Transport Ammonium Transport Positive Regulation Of Ion Transmembrane Transport Establishment Of Protein Localization To Plasma Membrane Monocarboxylic Acid Transport Regulation Of Anion Transport Protein Localization To Plasma Membrane Positive Regulation Of Intracellular Protein Transport Positive Regulation Of Ion Transport Plasma Membrane Organization Establishment Of Protein Localization To Membrane Positive Regulation Of Intracellular Transport Regulation Of Intracellular Protein Transport Inorganic Anion Transport Carboxylic Acid Transport Organic Acid Transport Positive Regulation Of Protein Transport Protein Localization To Membrane Regulation Of Ion Transmembrane Transport Endomembrane System Organization Regulation Of Intracellular Transport Organic Anion Transport Response To Drug Regulation Of Protein Transport Regulation Of Ion Transport Monovalent Inorganic Cation Transport Anion Transport Regulation Of Establishment Of Protein Localization Cell Proliferation Positive Regulation Of Transport
Tagcloud ?		causative collaborative determinant diminishes dysfunctional exon expand glut9 hypouricemia institutional japan japanese micc missense mutational pathogenic r198c r380w rhuc rhuc1 rhuc2 sua topology transporter urat1 urate uric urolithiasis