DIS3L

Gene Name		DIS3 like exosome 3-5 exoribonuclease
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Exosome (RNase Complex) Cytoplasm Centrosome Plasma Membrane
	Molecular Function	3'-5'-exoribonuclease Activity RNA Binding Protein Binding Enzyme Binding
	Biological Process	RRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: PAXIP1
Entrez ID		115752
HPRD ID		11355
Ensembl ID		ENSG00000166938
Uniprot IDs		Q8TF46
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Histone H3-K36 Methylation Chorion Development Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of DNA-templated Transcription, Initiation Positive Regulation Of Histone Acetylation Regulation Of DNA-templated Transcription, Initiation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Isotype Switching Positive Regulation Of Protein Acetylation Histone H3-K4 Methylation Regulation Of Isotype Switching Positive Regulation Of Immunoglobulin Mediated Immune Response Adipose Tissue Development Positive Regulation Of Histone Methylation Positive Regulation Of Immunoglobulin Production Regulation Of Histone Acetylation Regulation Of Histone Methylation Regulation Of DNA Recombination Positive Regulation Of Histone Modification Positive Regulation Of B Cell Activation DNA Damage Response, Signal Transduction By P53 Class Mediator Endothelial Cell Migration Histone Lysine Methylation Signal Transduction In Response To DNA Damage Peptidyl-lysine Methylation Vasculogenesis Epithelial Cell Migration Epithelium Migration Signal Transduction By P53 Class Mediator Histone Methylation Regulation Of Histone Modification Positive Regulation Of Protein Ubiquitination Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Positive Regulation Of Adaptive Immune Response Positive Regulation Of Protein Complex Assembly Protein Methylation Ameboidal-type Cell Migration Regulation Of Adaptive Immune Response Regulation Of Protein Ubiquitination Regulation Of Chromosome Organization DNA Recombination Connective Tissue Development Peptidyl-lysine Modification Positive Regulation Of Cell Activation Positive Regulation Of Cellular Component Biogenesis Regulation Of Protein Complex Assembly Regulation Of Lymphocyte Activation
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