ARHGAP33

Description		Rho GTPase activating protein 33
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Cell Cortex Postsynaptic Density Actin Cytoskeleton Protein-containing Complex Dendritic Spine Glutamatergic Synapse
	Molecular Function	GTPase Activator Activity Protein Binding Protein Kinase Binding Phosphatidylinositol Binding
	Biological Process	Signal Transduction Small GTPase-mediated Signal Transduction Response To Toxic Substance Protein Transport Regulation Of Dendritic Spine Morphogenesis Regulation Of Postsynapse Assembly
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle RHOQ GTPase cycle
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Umami taste perception in obesity with metabolic syndrome ( 31005965) Urinary albumin-to-creatinine ratio ( 26631737)
Interacting Genes		5 interacting genes: CYSRT1 FYN KRTAP10-8 NEK6 RAC1
Entrez ID		115703
HPRD ID		15415
Ensembl ID		ENSG00000004777
Uniprot IDs		A1A5D2 O14559
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Hydrogen Peroxide Metabolic Process Dendrite Morphogenesis Regulation Of Neuron Migration Positive Regulation Of Protein Localization To Membrane Actin Filament Cellular Response To Glycine Forebrain Development Response To Singlet Oxygen Response To Glycine Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Postsynapse Organization Regulation Of Cell Shape Neuron Migration Positive Regulation Of Ovarian Follicle Development Negative Regulation Of Interleukin-23 Production Regulation Of ERK5 Cascade Angiotensin-activated Signaling Pathway Involved In Heart Process Embryonic Olfactory Bulb Interneuron Precursor Migration Cerebral Cortex GABAergic Interneuron Development Negative Regulation Of Hydrogen Peroxide Biosynthetic Process Rho GDP-dissociation Inhibitor Binding Regulation Of Cell Adhesion Involved In Heart Morphogenesis Regulation Of Protein Localization To Membrane CD8 Receptor Binding Neuron Projection Guidance Negative Regulation Of Hydrogen Peroxide Metabolic Process Negative Regulation Of Dendritic Spine Maintenance Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Type 5 Metabotropic Glutamate Receptor Binding Growth Factor Receptor Binding Axon Guidance Regulation Of Ovarian Follicle Development Auditory Receptor Cell Morphogenesis Erythrocyte Enucleation Engulfment Of Apoptotic Cell Tangential Migration From The Subventricular Zone To The Olfactory Bulb Cell Projection Morphogenesis Neuron Projection Morphogenesis Cellular Response To L-glutamate Positive Regulation Of Intracellular Signal Transduction CD4 Receptor Binding Regulation Of Cell Morphogenesis Activated T Cell Proliferation Kinocilium G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Regulation Of Neuron Maturation Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Hepatocyte Growth Factor Receptor Signaling Pathway Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Regulation Of Synapse Organization
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