CARD16

Description		caspase recruitment domain family member 16
Image		No pdb structure
GO Annotations	Cellular Component	Protein-containing Complex Protease Inhibitor Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Enzyme Binding Kinase Binding Peptidase Inhibitor Activity Identical Protein Binding CARD Domain Binding Caspase Binding
	Biological Process	Proteolysis Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Protein Binding Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-1 Beta Production Regulation Of Apoptotic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Cellular Response To Lipopolysaccharide
Pathways
Drugs
Diseases
GWAS
Interacting Genes		5 interacting genes: CARD17P CARD8 CASP1 RIPK2 UBC
Entrez ID		114769
HPRD ID		16740
Ensembl ID		ENSG00000204397
Uniprot IDs		Q5EG05
PDB IDs
Enriched GO Terms of Interacting Partners?		CARD Domain Binding Regulation Of Interleukin-1 Beta Production Regulation Of Interleukin-1 Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production NLRP3 Inflammasome Complex Caspase Binding Canonical Inflammasome Complex Pyroptotic Cell Death Cellular Response To Lipopolysaccharide Regulation Of Cytokine-mediated Signaling Pathway Cellular Response To Molecule Of Bacterial Origin Activation Of Innate Immune Response Protein-containing Complex Regulation Of Cytokine Production Negative Regulation Of Interleukin-1 Beta Production Response To Lipopolysaccharide Positive Regulation Of Innate Immune Response Negative Regulation Of Interleukin-1 Production Pyroptotic Inflammatory Response Regulation Of Canonical NF-kappaB Signal Transduction Response To Molecule Of Bacterial Origin Proteolysis Positive Regulation Of Cytokine-mediated Signaling Pathway Activation Of Immune Response Cysteine-type Endopeptidase Activity Protein Metabolic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Response To External Biotic Stimulus Positive Regulation Of Response To Cytokine Stimulus Regulation Of Innate Immune Response Positive Regulation Of Defense Response Cellular Response To Lipid Regulation Of Apoptotic Process Positive Regulation Of Cytokine Production Regulation Of Programmed Cell Death Endopeptidase Activity Inflammatory Response CARD8 Inflammasome Complex Negative Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Immune Response AIM2 Inflammasome Complex Assembly Protease Inhibitor Complex NACHT Domain Binding AIM2 Inflammasome Complex IPAF Inflammasome Complex Response To Interleukin-18 Pattern Recognition Receptor Signaling Pathway Response To Lipid Positive Regulation Of Inflammatory Response
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