UCN3

Description		urocortin 3
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Axon Varicosity Axon Terminus
	Molecular Function	Signaling Receptor Binding Hormone Activity Protein Binding Corticotropin-releasing Hormone Receptor Binding Corticotropin-releasing Hormone Receptor 2 Binding
	Biological Process	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Digestion Response To Glucose Hormone-mediated Signaling Pathway Cellular Response To Nutrient Levels Positive Regulation Of Insulin Secretion Response To Immobilization Stress Response To Starvation Positive Regulation Of Membrane Potential Response To Corticosterone Cellular Response To Hypoxia
Pathways		Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Intelligence ( 22449649)
Interacting Genes		3 interacting genes: CRHR1 CRHR2 IL10RB
Entrez ID		114131
HPRD ID		12066
Ensembl ID		ENSG00000178473
Uniprot IDs		Q969E3
PDB IDs		2RMH 3N93
Enriched GO Terms of Interacting Partners?		Corticotropin-releasing Hormone Receptor Activity Corticotrophin-releasing Factor Receptor Activity Cellular Response To Corticotropin-releasing Hormone Stimulus G Protein-coupled Peptide Receptor Activity Cellular Response To Peptide Hormone Stimulus Corticotropin-releasing Hormone Binding Hormone-mediated Signaling Pathway Corticotropin Secretion Interleukin-10 Receptor Activity Transmembrane Signaling Receptor Activity Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Interleukin-28 Receptor Complex General Adaptation Syndrome, Behavioral Process Response To Peptide Hormone Regulation Of Corticosterone Secretion Cellular Response To Hormone Stimulus G Protein-coupled Receptor Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Parturition Behavioral Response To Ethanol Cell Surface Receptor Signaling Pathway Type III Interferon-mediated Signaling Pathway Interleukin-10-mediated Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of Cellular Respiration Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Lyase Activity Positive Regulation Of Cyclase Activity Response To Hormone Adrenal Gland Development Negative Regulation Of Transporter Activity G Protein-coupled Receptor Signaling Pathway Exploration Behavior Negative Regulation Of Calcium Ion Transmembrane Transport Peptide Hormone Binding Fear Response Regulation Of Cell Communication Cellular Response To Oxygen-containing Compound Regulation Of Signaling Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Receptor Signaling Pathway Via STAT Regulation Of Cellular Respiration Negative Regulation Of Calcium Ion Transport Long-term Synaptic Potentiation Axon Terminus Coreceptor Activity Peptide Hormone Secretion Negative Regulation Of Cation Transmembrane Transport Multicellular Organismal Response To Stress
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