TUSC2

Description		tumor suppressor 2, mitochondrial calcium regulator
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion
	Molecular Function	Protein Binding
	Biological Process	Natural Killer Cell Differentiation Phagocytosis Inflammatory Response Negative Regulation Of Interleukin-17 Production Positive Regulation Of Interleukin-10 Production Cell Maturation Defense Response To Gram-negative Bacterium Regulation Of Mitochondrial Membrane Potential Neutrophil-mediated Killing Of Gram-negative Bacterium Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		5 interacting genes: FHL5 MAPK9 MDFI NEDD4 RBPMS
Entrez ID		11334
HPRD ID		06134
Ensembl ID		ENSG00000114383
Uniprot IDs		O75896
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Channel Inhibitor Activity Phosphoserine Residue Binding Nuclear Receptor-mediated Corticosteroid Signaling Pathway Beta-2 Adrenergic Receptor Binding Phosphothreonine Residue Binding Positive Regulation Of Protein Catabolic Process Negative Regulation Of Potassium Ion Export Across Plasma Membrane Formation Of Structure Involved In A Symbiotic Process JUN Kinase Activity Protein Localization To Tricellular Tight Junction MRNA CDS Binding Regulation Of Primary Metabolic Process Dorsal/ventral Axis Specification Regulation Of Macromolecule Metabolic Process Trophoblast Giant Cell Differentiation Sodium Channel Inhibitor Activity Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Sodium Ion Transport Regulation Of Potassium Ion Export Across Plasma Membrane Progesterone Receptor Signaling Pathway Endocardial Cushion Development Response To Metal Ion Potassium Channel Inhibitor Activity Positive Regulation Of Podosome Assembly Regulation Of Podosome Assembly Regulation Of MRNA Metabolic Process Inflammatory Response To Wounding Transcription Coactivator Activity Pre-mRNA Intronic Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Protein Catabolic Process MAP Kinase Activity Response To Oxidative Stress
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