KIF12

Description		kinesin family member 12
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Kinesin Complex Microtubule Organelle Extracellular Exosome
	Molecular Function	Nucleotide Binding Microtubule Motor Activity ATP Binding Microtubule Binding ATP Hydrolysis Activity
	Biological Process	Microtubule-based Movement
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Tourette syndrome ( 22889924)
Interacting Genes		3 interacting genes: CFTR FBXO7 LMNA
Entrez ID		113220
HPRD ID		13914
Ensembl ID		ENSG00000136883
Uniprot IDs		A0A1W2PPS5 Q96FN5
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Positive Regulation Of Anion Channel Activity DNA Double-strand Break Attachment To Nuclear Envelope Structural Constituent Of Nuclear Lamina Positive Regulation Of Monoatomic Anion Transport Negative Regulation Of Apoptotic Signaling Pathway Lewy Body Core Positive Regulation Of Enamel Mineralization Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Transepithelial Water Transport Lamin Filament Nuclear Pore Localization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Regulation Of Protein Stability Establishment Of Protein Localization To Organelle Negative Regulation Of Mesenchymal Cell Proliferation Amelogenesis Regulation Of Apoptotic Signaling Pathway ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Ventricular Cardiac Muscle Cell Development Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Regulation Of Monoatomic Anion Transport Organelle Localization Epithelial Fluid Transport Nuclear Lamina Golgi-associated Vesicle Membrane Protein Localization To Nuclear Envelope Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Forskolin Response To Forskolin Negative Regulation Of Release Of Cytochrome C From Mitochondria Chloride Transmembrane Transporter Activity Regulation Of Biological Quality Sperm Capacitation Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Nuclear Envelope Organization Bicarbonate Transport
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