MGAT4B

Gene Name		mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane
	Molecular Function	Alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase Activity Metal Ion Binding
	Biological Process	N-glycan Processing Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Diseases of glycosylation Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MOGS causes MOGS-CDG (CDG-2b) N-Glycan antennae elongation N-glycan antennae elongation in the medial/trans-Golgi Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Post-translational protein modification Defective ALG3 causes ALG3-CDG (CDG-1d) Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective RFT1 causes RFT1-CDG (CDG-1n) Defective ALG6 causes ALG6-CDG (CDG-1c) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: LRSAM1
Entrez ID		11282
HPRD ID		05190
Ensembl ID		ENSG00000161013
Uniprot IDs		Q9UQ53
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin-dependent Endocytosis Viral Budding Virion Assembly Protein Autoubiquitination Negative Regulation Of Endocytosis Membrane Budding Protein Polyubiquitination Regulation Of Endocytosis Viral Life Cycle Vesicle Organization
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