KLF12

Gene Name		Kruppel-like factor 12
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Pancreatic cancer ( 20101243) Phospholipid levels (plasma) ( 22359512) Ventricular conduction ( 21076409)
Protein-protein Interactions		4 interactors: APP CTBP1 EHMT2 THAP1
Entrez ID		11278
HPRD ID		06336
Ensembl ID		ENSG00000118922
Uniprot IDs		Q8WWI3 Q9Y4X4
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Regulation Of Cell Cycle Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury DNA Methylation On Cytosine Within A CG Sequence Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Neuron Remodeling Negative Regulation Of Histone H4 Acetylation Histone H3-K27 Methylation Histone Modification Regulation Of Cellular Amino Acid Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Peptidyl-lysine Dimethylation Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process DNA Methylation On Cytosine Growth Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Histone H4 Acetylation White Fat Cell Differentiation Endothelial Cell Proliferation Nitrogen Compound Metabolic Process Cellular Copper Ion Homeostasis Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Deacetylation Histone H3-K9 Methylation Chromatin Modification Copper Ion Homeostasis Suckling Behavior Negative Regulation Of Peptidyl-lysine Acetylation Synaptonemal Complex Assembly Negative Regulation Of Protein Acetylation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Synaptonemal Complex Organization Viral Genome Replication Positive Regulation Of Protein Deacetylation Neuron Maturation
Tagcloud ?		aberrations arrays caucasian cdkn2a cna cnas copy curative decades deleted discovered driver eac esophageal esophagectomy fhit frequent gistic heterozygosity intent oncogenes ptprd regions residing smad4 snp stratified suitable targetable