ADCY6

Name	adenylate cyclase 6
Structure	No pdb structure
Interactors	4 interactors: ATXN1 CHRNA7 GNAS RAF1
GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane Stereocilium Cell Projection
	Molecular Function	Nucleotide Binding Adenylate Cyclase Activity Protein Kinase C Binding Protein Binding ATP Binding Lyase Activity Phosphorus-oxygen Lyase Activity Protein Kinase Binding Metal Ion Binding
	Biological Process	Renal Water Homeostasis CAMP Biosynthetic Process Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Adenylate Cyclase-activating Serotonin Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway Cyclic Nucleotide Biosynthetic Process Negative Regulation Of Neuron Projection Development Intracellular Signal Transduction Negative Regulation Of Urine Volume Cellular Response To Prostaglandin E Stimulus Cellular Response To Catecholamine Stimulus Blood Vessel Diameter Maintenance Cellular Response To Vasopressin Cellular Response To Forskolin
Pathways	Glucagon signaling in metabolic regulation PKA activation PKA activation in glucagon signalling Adenylate cyclase activating pathway Adenylate cyclase inhibitory pathway Adenylate cyclase inhibitory pathway Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Adrenaline,noradrenaline inhibits insulin secretion G alpha (s) signalling events G alpha (s) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events Vasopressin regulates renal water homeostasis via Aquaporins Hedgehog 'off' state GPER1 signaling GPER1 signaling ADORA2B mediated anti-inflammatory cytokines production ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Drugs	Colforsin
GWAS	Clozapine-induced agranulocytosis ( 25187353 ) Height ( 28552196 )
Entrez ID	112
HPRD ID	02621
Ensembl ID	ENSG00000174233
Uniprot IDs	O43306
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Adenylate Cyclase Activator Activity Cognition Insulin-like Growth Factor Receptor Signaling Pathway Excitatory Postsynaptic Potential Memory Regulation Of Postsynaptic Membrane Potential Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Regulation Of Biological Quality Nervous System Process Chemical Homeostasis Regulation Of Developmental Process Mu-type Opioid Receptor Binding Death-inducing Signaling Complex Assembly Synaptic Transmission Involved In Micturition Regulation Of Signal Transduction Sensory Processing Corticotropin-releasing Hormone Receptor 1 Binding Adenylate Cyclase Regulator Activity POZ Domain Binding Postsynapse Hair Follicle Placode Formation Adenylate Cyclase-activating Serotonin Receptor Signaling Pathway Negative Regulation Of Signal Transduction Acetylcholine Binding Learning Or Memory Positive Regulation Of Metabolic Process Regulation Of Cell Communication Dendrite Arborization Neurotransmitter Receptor Complex Short-term Memory Toxic Substance Binding Negative Regulation Of Cell Communication Homeostatic Process Chloride Channel Regulator Activity Regulation Of Signaling Response To Acetylcholine Negative Regulation Of Signaling Negative Regulation Of 3'-UTR-mediated MRNA Stabilization System Process D1 Dopamine Receptor Binding Cellular Response To Glucagon Stimulus Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Beta-2 Adrenergic Receptor Binding Animal Organ Development Establishment Of Localization In Cell Serotonin Receptor Signaling Pathway Vascular Endothelial Cell Response To Laminar Fluid Shear Stress Insulin Secretion Involved In Cellular Response To Glucose Stimulus