ABCB8

Gene Name		ATP-binding cassette, sub-family B (MDR/TAP), member 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Mitochondrion Mitochondrial Envelope Mitochondrial Inner Membrane Membrane Integral Component Of Membrane ATP-binding Cassette (ABC) Transporter Complex
	Molecular Function	Transporter Activity ATP Binding ATPase Activity, Coupled To Transmembrane Movement Of Substances
	Biological Process	Transport Metabolic Process Transmembrane Transport
Pathways		Mitochondrial ABC transporters ABC-family proteins mediated transport
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: NOA1 SAT1
Entrez ID		11194
HPRD ID		10400
Ensembl ID		ENSG00000197150
Uniprot IDs		A5D8W3 B4DG02 G3XAP3 Q9NUT2
PDB IDs
Enriched GO Terms of Interacting Partners?		Spermidine Acetylation Putrescine Catabolic Process Oxalate Transport Polyamine Catabolic Process 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process Regulation Of Cellular Respiration Neurotransmitter Uptake 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Polyamine Biosynthetic Process Amine Biosynthetic Process Polyamine Metabolic Process Sulfate Transmembrane Transport Sulfate Transport Neutral Amino Acid Transport Regulation Of Generation Of Precursor Metabolites And Energy Mitochondrial Translation Dicarboxylic Acid Transport Chloride Transmembrane Transport Amino Acid Transmembrane Transport Cellular Biogenic Amine Metabolic Process Chloride Transport Amine Metabolic Process Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Regulation Of Neurotransmitter Levels Response To Xenobiotic Stimulus Amino Acid Transport Neurotransmitter Transport Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Glycosaminoglycan Metabolic Process Ribosome Biogenesis Sodium Ion Transmembrane Transport Pathogenesis Purine Nucleoside Metabolic Process
Tagcloud ?		abcb1 abcb5 abcc1 abcc3 abcc5 abcg2 bcrp canine cassette cytostatic demographics dogs doxorubicin efflux glucocorticoids hypercalcaemia lymphoma lymphomas mrp1 multicentric multidrug protocol quantified staging substage transporter tumour typically