KPTN

Description		kaptin, actin binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Actin Cytoskeleton Membrane Lamellipodium Filamentous Actin Stereocilium Cell Projection Postsynaptic Actin Cytoskeleton Glutamatergic Synapse KICSTOR Complex
	Molecular Function	Actin Binding Protein Binding Actin Filament Binding
	Biological Process	Actin Filament Organization Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Protein Localization To Lysosome Negative Regulation Of TORC1 Signaling
Pathways		Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Walking pace ( 33128006)
Interacting Genes		3 interacting genes: ACTC1 APP SRPK1
Entrez ID		11133
HPRD ID		17241
Ensembl ID		ENSG00000118162
Uniprot IDs		A0A384NLB4 Q9Y664
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Body Cytoplasmic Actin-based Contraction Involved In Cell Motility Mesenchyme Migration Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Skeletal Muscle Thin Filament Assembly Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Actin-myosin Filament Sliding Heart Contraction Cardiac Myofibril Assembly Cellular Component Assembly Supramolecular Fiber Organization Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding
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