CLASRP

Description		CLK4 associating serine/arginine rich protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm
	Molecular Function	Protein Binding
	Biological Process	MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)
Interacting Genes		14 interacting genes: APP ATXN1 CDK6 CLK1 CLK2 CLK3 CLK4 DAB1 DAZAP2 DYRK1A RHOXF2 SMAD3 SRPK2 VDR
Entrez ID		11129
HPRD ID		11552
Ensembl ID		ENSG00000104859
Uniprot IDs		Q8N2M8
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Serine/threonine/tyrosine Kinase Activity Protein Serine Kinase Activity Regulation Of RNA Splicing Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Protein Kinase Activity Kinase Activity Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Nuclear Speck Positive Regulation Of Gene Expression Identical Protein Binding Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Adult Locomotory Behavior ATP Binding Positive Regulation Of Biosynthetic Process Protein Phosphorylation Protein Serine/threonine Kinase Binding Positive Regulation Of Macromolecule Metabolic Process Nucleotide Binding Transferase Activity Phosphorylation Negative Regulation Of MiRNA Transcription Adult Behavior Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Cell Differentiation Locomotory Behavior Negative Regulation Of RNA Metabolic Process Receptor Complex Positive Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Bone Mineralization Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Negative Regulation Of Transcription By RNA Polymerase II Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Dendrite Development Cyclin D2-CDK6 Complex Non-membrane Spanning Protein Tyrosine Kinase Activity Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration
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