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HIBADH
Gene Name
3-hydroxyisobutyrate dehydrogenase
Image
Gene Ontology Annotations
Cellular Component
Mitochondrial Matrix
Molecular Function
Phosphogluconate Dehydrogenase (decarboxylating) Activity
3-hydroxyisobutyrate Dehydrogenase Activity
NAD Binding
Biological Process
Pentose-phosphate Shunt
Valine Catabolic Process
Branched-chain Amino Acid Catabolic Process
Cellular Nitrogen Compound Metabolic Process
Small Molecule Metabolic Process
Pathways
Branched-chain amino acid catabolism
Metabolism of amino acids and derivatives
Drugs
NADH
Diseases
GWAS
Protein-protein Interactions
2 interactors:
BRCA1
TRIM63
Entrez ID
11112
HPRD ID
12238
Ensembl ID
ENSG00000106049
Uniprot IDs
P31937
PDB IDs
2GF2
2I9P
Enriched GO Terms of Interacting Partners
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Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Positive Regulation Of Histone H3-K9 Acetylation
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Cellular Response To Organic Cyclic Compound
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Cellular Response To Indole-3-methanol
Response To Steroid Hormone
Negative Regulation Of Centriole Replication
Skeletal Muscle Atrophy
Dosage Compensation By Inactivation Of X Chromosome
Striated Muscle Atrophy
Protein Ubiquitination
Protein K6-linked Ubiquitination
Muscle Atrophy
Protein Modification By Small Protein Conjugation
Regulation Of Histone H3-K9 Acetylation
Negative Regulation Of Histone H3-K9 Methylation
Positive Regulation Of Histone H3-K9 Methylation
Dosage Compensation
Skeletal Muscle Adaptation
Response To Cytokine
Regulation Of Centriole Replication
Positive Regulation Of Histone H3-K4 Methylation
Regulation Of Histone H4 Acetylation
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Negative Regulation Of Fatty Acid Biosynthetic Process
DNA Damage Response, Signal Transduction Resulting In Transcription
Negative Regulation Of Histone Methylation
Response To Lipid
Negative Regulation Of Centrosome Duplication
Regulation Of DNA Methylation
Negative Regulation Of Histone Acetylation
Response To Organic Cyclic Compound
Positive Regulation Of Histone Acetylation
Negative Regulation Of Peptidyl-lysine Acetylation
Regulation Of Histone H3-K4 Methylation
Response To Hormone
Negative Regulation Of Protein Acetylation
Positive Regulation Of Peptidyl-lysine Acetylation
Positive Regulation Of Protein Acetylation
Postreplication Repair
Regulation Of Transcription From RNA Polymerase III Promoter
Negative Regulation Of Fatty Acid Metabolic Process
Regulation Of Gene Expression By Genetic Imprinting
Response To Abiotic Stimulus
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Genetic Imprinting
Cellular Response To Dexamethasone Stimulus
Tagcloud
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5k3
alpl
armitage
beadchip
bovinesnp50
bull
capn1
catsper1
cohran
dehygrogenase
ethanolamine
etnk1
friesian
goldenhelix
hydroxyisobutyrate
kelch
klhl1
loc785875
mc4r
pdzrn4
prkcb
rs110596818
rs110827324
rs110876480
rs29011704
sire
srd5a2
svs7
trim36