ADAMTS13

Gene Name		ADAM metallopeptidase with thrombospondin type 1 motif, 13
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Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Extracellular Space Endoplasmic Reticulum Lumen Cell Surface
	Molecular Function	Metalloendopeptidase Activity Integrin Binding Calcium Ion Binding Protein Binding Metallopeptidase Activity Zinc Ion Binding
	Biological Process	Protein O-linked Glycosylation Proteolysis Cell-matrix Adhesion Integrin-mediated Signaling Pathway Glycoprotein Metabolic Process Response To Toxic Substance Protein Processing Platelet Activation Response To Interferon-gamma Response To Tumor Necrosis Factor Protein O-linked Fucosylation Peptide Catabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process Response To Interleukin-4
Pathways		Post-translational protein modification O-glycosylation of TSR domain-containing proteins O-linked glycosylation
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Coagulation factor levels ( 23267103) Liver enzyme levels ( 18940312)
Protein-protein Interactions		1 interactors: VWF
Entrez ID		11093
HPRD ID		04994
Ensembl ID		ENSG00000160323
Uniprot IDs		Q76LX8
PDB IDs		3GHM 3GHN 3VN4
Enriched GO Terms of Interacting Partners?		Blood Coagulation, Intrinsic Pathway
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