SERINC3

Description		serine incorporator 3
Image
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding L-serine Transmembrane Transporter Activity Phospholipid Scramblase Activity
	Biological Process	Immune System Process L-serine Biosynthetic Process L-serine Transport Plasma Membrane Phospholipid Scrambling Innate Immune Response Defense Response To Virus Antiviral Innate Immune Response Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways		Serine metabolism
Drugs
Diseases
GWAS		Bipolar disorder ( 22925353) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 21297633 28067908)
Novel Interacting Genes		1 novel interacting genes: ATXN7
Interacting Genes		4 interacting genes: AGTR1 BMP10 DRD2 RPS15
Entrez ID		10955
HPRD ID		06201
Ensembl ID		ENSG00000132824
Uniprot IDs		Q13530
PDB IDs		7RU6 7RUG
Enriched GO Terms of Interacting Partners?		Regulation Of Renal Sodium Excretion Regulation Of Blood Circulation Kidney Development Regulation Of Hormone Secretion Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Cellular Component Organization Positive Regulation Of Cell Population Proliferation Regulation Of Growth Regulation Of Blood Pressure Angiotensin Type I Receptor Activity Angiotensin Type II Receptor Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Regulation Of System Process Phospholipase C-activating Angiotensin-activated Signaling Pathway Bradykinin Receptor Binding Positive Regulation Of Cell Differentiation Renal System Process Renin-angiotensin Regulation Of Aldosterone Production Regulation Of Synapse Structural Plasticity Dopamine Binding Dopamine Neurotransmitter Receptor Activity Cerebral Cortex GABAergic Interneuron Migration Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Growth Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway G Protein-coupled Receptor Complex Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Negative Regulation Of Dephosphorylation Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Hyaloid Vascular Plexus Regression Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Interneuron Migration From The Subpallium To The Cortex Branching Morphogenesis Of A Nerve Negative Regulation Of Dopamine Secretion Positive Regulation Of Neurotransmitter Uptake Regulation Of Heart Contraction Regulation Of Dopamine Uptake Involved In Synaptic Transmission Heterotrimeric G-protein Binding Regulation Of Locomotion Involved In Locomotory Behavior Negative Regulation Of Dopamine Receptor Signaling Pathway Positive Regulation Of Developmental Growth Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure Phospholipase C-activating Dopamine Receptor Signaling Pathway Ribosomal Small Subunit Export From Nucleus Positive Regulation Of Sarcomere Organization Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Tagcloud ?