MSL3

Gene Name		male-specific lethal 3 homolog (Drosophila)
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm MSL Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Methylated Histone Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Histone H4-K16 Acetylation
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-protein Interactions		8 interactors: APP CDK6 HIST1H3A HIST1H4A HIST3H3 HIST4H4 KAT8 PAF1
Entrez ID		10943
HPRD ID		05344
Ensembl ID		ENSG00000005302
Uniprot IDs		B7Z227 Q8N5Y2
PDB IDs		2Y0N 3OA6 3OB9
Enriched GO Terms of Interacting Partners?		DNA Replication-dependent Nucleosome Assembly DNA Methylation On Cytosine Negative Regulation Of Myeloid Cell Differentiation Chromatin Silencing At RDNA Chromatin Silencing Chromosome Organization Regulation Of Myeloid Cell Differentiation Histone H4-K20 Demethylation DNA Methylation Negative Regulation Of Megakaryocyte Differentiation Chromatin Organization Negative Regulation Of Cell Differentiation Negative Regulation Of Gene Expression, Epigenetic Telomere Maintenance DNA Modification Negative Regulation Of Immune System Process Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Gene Silencing Histone Modification Nucleosome Assembly Chromatin Assembly Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Nucleosome Organization Negative Regulation Of RNA Biosynthetic Process Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly Regulation Of Megakaryocyte Differentiation DNA Packaging Negative Regulation Of Gene Expression Chromatin Modification Negative Regulation Of Biosynthetic Process Homeostatic Process CENP-A Containing Nucleosome Assembly Regulation Of Gene Expression, Epigenetic MRNA Polyadenylation Regulation Of Hematopoietic Progenitor Cell Differentiation Histone Exchange DNA Replication-independent Nucleosome Assembly Histone Lysine Demethylation Regulation Of Cell Differentiation Histone Demethylation RNA Polyadenylation Nucleobase-containing Compound Metabolic Process Protein Demethylation DNA Conformation Change Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression
Tagcloud ?		achieve analyze chip chromodomain chromodomains compensation counterparts disruption dosage drosophila entry flanking h3k36me3 lethal marked melanogaster mutants nucleosomal nucleosomes preferential respective retain similarly spread spreading targeting trimethylation upregulates