FGL2

Description		fibrinogen like 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Fibrinogen Complex Extracellular Space Extracellular Matrix Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding
	Biological Process	T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Negative Regulation Of Macrophage Antigen Processing And Presentation Negative Regulation Of Memory T Cell Differentiation Negative Regulation Of Defense Response To Virus
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Crohn's disease ( 30500874)
Novel Interacting Genes		1 novel interacting genes: ATP2A2
Interacting Genes		1 interacting genes: CFTR
Entrez ID		10875
HPRD ID		16098
Ensembl ID		ENSG00000127951
Uniprot IDs		A4D1B8 Q14314
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Docking Organelle Localization By Membrane Tethering P-type Calcium Transporter Activity Involved In Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of Exocytosis Longitudinal Sarcoplasmic Reticulum Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Calcium Ion-transporting ATPase Complex Response To Endoplasmic Reticulum Stress Positive Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Calcium Ion Transport From Cytosol To Endoplasmic Reticulum Positive Regulation Of Anion Channel Activity Calcium Ion Import Into Sarcoplasmic Reticulum Positive Regulation Of Monoatomic Anion Transport Enzyme Binding Mitochondrion-endoplasmic Reticulum Membrane Tethering Organelle Localization Ribbon Synapse Monoatomic Ion Homeostasis Intracellular Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of Membrane Potential Autophagosome Membrane Docking Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter ATP Hydrolysis Activity Transition Between Fast And Slow Fiber Intracellular Monoatomic Cation Homeostasis T-tubule Organization Cytosol To Endoplasmic Reticulum Transport Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Intracellular Chemical Homeostasis P-type Calcium Transporter Activity Platelet Dense Tubular Network Membrane Regulation Of Vesicle-mediated Transport Amelogenesis Regulation Of Secretion By Cell ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Skeletal Muscle Adaptation Regulation Of Secretion
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