ALDH1L1

Description		aldehyde dehydrogenase 1 family member L1
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Extracellular Exosome
	Molecular Function	Catalytic Activity Aldehyde Dehydrogenase (NAD+) Activity Protein Binding Formyltetrahydrofolate Dehydrogenase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The Aldehyde Or Oxo Group Of Donors, NAD Or NADP As Acceptor
	Biological Process	One-carbon Metabolic Process NADPH Regeneration 10-formyltetrahydrofolate Catabolic Process Tetrahydrofolate Interconversion
Pathways		Metabolism of folate and pterines
Drugs		Tetrahydrofolic acid
Diseases
GWAS		Glycine levels ( 31070104) Liver enzyme levels (alanine transaminase) ( 33972514) Macular telangiectasia type 2 ( 28250457) Male-pattern baldness ( 28196072) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Metabolite levels ( 23378610) Multiple sclerosis ( 31604244) Plasma homocysteine levels (post-methionine load test) ( 24651765) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Waist circumference ( 28552196)
Interacting Genes		1 interacting genes: APPBP2
Entrez ID		10840
HPRD ID		02594
Ensembl ID		ENSG00000144908
Uniprot IDs		O75891 Q53H87
PDB IDs		2BW0 2CFI 2CQ8 7YJJ
Enriched GO Terms of Interacting Partners?		Cul2-RING Ubiquitin Ligase Complex
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