ARPP21

Description		cAMP regulated phosphoprotein 21
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Nucleic Acid Binding Protein Binding Calmodulin Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Asthma ( 29273806) Feeling worry ( 29500382) General cognitive ability ( 29844566) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Hand grip strength ( 29691431) Irritable mood ( 29500382) Neurociticism ( 29500382) Severe influenza A (H1N1) infection ( 26379185) Tea consumption ( 31046077) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		2 interacting genes: TERF1 TERF2IP
Entrez ID		10777
HPRD ID		09265
Ensembl ID		ENSG00000172995
Uniprot IDs		A0A804HI65 A8K0T4 A8K1F3 Q9UBL0
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Telomere Cap Complex Shelterin Complex G-rich Strand Telomeric DNA Binding Telomere Capping Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Telomeric DNA Binding Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization DNA Biosynthetic Process Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Telomere Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Chromosome, Telomeric Region Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Chromosome Organization Negative Regulation Of DNA Recombination At Telomere Positive Regulation Of DNA Metabolic Process Chromosome Organization Nuclear Body Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of DNA Metabolic Process Telomerase Activity Ankyrin Repeat Binding Protection From Non-homologous End Joining At Telomere Positive Regulation Of Organelle Organization Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Telomere Localization Telomeric D-loop Disassembly Double-stranded Telomeric DNA Binding Telomeric Loop Disassembly Protein Localization To Chromosome, Telomeric Region T-circle Formation Chromosome Telomere Maintenance In Response To DNA Damage Negative Regulation Of Cellular Component Organization DNA Metabolic Process DNA Binding, Bending Negative Regulation Of Telomere Maintenance Via Telomerase
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