NUDC

Description		nuclear distribution C, dynein complex regulator
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Spindle Cytosol Cytoskeleton Microtubule Midbody Mitotic Spindle
	Molecular Function	Protein Binding Cadherin Binding Unfolded Protein Binding
	Biological Process	Protein Folding Mitotic Spindle Organization Mitotic Metaphase Chromosome Alignment Nuclear Migration Response To Peptide Hormone Cell Division Establishment Of Organelle Localization
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation RND2 GTPase cycle
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Lipoprotein (a) levels ( 33730874) Plateletcrit ( 27863252)
Novel Interacting Genes		2 novel interacting genes: HPCA TUBE1
Interacting Genes		8 interacting genes: ACD CEBPA NAGK OGT PAFAH1B1 PLK1 POT1 TINF2
Entrez ID		10726
HPRD ID		10122
Ensembl ID		ENSG00000090273
Uniprot IDs		Q9Y266
PDB IDs		3QOR 7NDX
Enriched GO Terms of Interacting Partners?		Telomere Assembly Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Negative Regulation Of Chromosome Organization Negative Regulation Of Telomere Maintenance Via Telomerase Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Metabolic Process Negative Regulation Of Cellular Component Organization Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Organelle Organization Regulation Of Chromosome Organization Positive Regulation Of Telomere Maintenance Microtubule Organizing Center Organization Regulation Of DNA Biosynthetic Process Protein Localization To Chromosome, Telomeric Region Telomere Maintenance Positive Regulation Of Chromosome Organization Protein Localization To Chromosome Chromosome Organization Regulation Of Telomere Maintenance Nuclear Membrane Disassembly Membrane Disassembly Telomere Organization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Telomere Maintenance Via Telomerase Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA-templated DNA Biosynthetic Process Regulation Of Cellular Component Organization Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA Metabolic Process Chromosome, Telomeric Region Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Intracellular Signal Transduction Establishment Of Mitotic Spindle Orientation Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Regulation Of Organelle Organization Protein Localization To Organelle Centrosome Cycle Nuclear Membrane Organization Microtubule Cytoskeleton
Tagcloud ?