CGREF1

Description		cell growth regulator with EF-hand domain 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Cell Adhesion Negative Regulation Of Cell Population Proliferation Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Left–right brain asymmetry ( 33723403) Response to cytadine analogues (cytosine arabinoside) ( 24483146) Self-reported risk-taking behaviour ( 30271922) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Novel Interacting Genes		2 novel interacting genes: RTN4 SC5D
Interacting Genes		2 interacting genes: AQP6 CFTR
Entrez ID		10669
HPRD ID		09365
Ensembl ID		ENSG00000138028
Uniprot IDs		Q99674
PDB IDs
Enriched GO Terms of Interacting Partners?		Fluid Transport Water Transport Cholesterol Biosynthetic Process Sterol Biosynthetic Process Nitrate Transmembrane Transporter Activity Chloride Transmembrane Transport Odontogenesis Chloride Transport Steroid Biosynthetic Process Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Delta7-sterol 5(6)-desaturase Activity Negative Regulation Of Vasculogenesis Positive Regulation Of ERBB3 Signaling Pathway Cell Adhesion Involved In Sprouting Angiogenesis Inorganic Anion Transmembrane Transport Cholesterol Metabolic Process Sterol Metabolic Process PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Monoatomic Anion Transmembrane Transport Inorganic Anion Transport Monoatomic Anion Transport Positive Regulation Of Anion Channel Activity C-5 Sterol Desaturase Activity Positive Regulation Of Monoatomic Anion Transport Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol Positive Regulation Of Protein Localization To Endoplasmic Reticulum Endoplasmic Reticulum Membrane Positive Regulation Of Enamel Mineralization Cell Migration Involved In Vasculogenesis Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Transepithelial Water Transport Steroid Metabolic Process Regulation Of Branching Morphogenesis Of A Nerve Intracellular Sphingolipid Homeostasis Central Nervous System Vasculogenesis Endoplasmic Reticulum Tubular Network Membrane Positive Regulation Of Tooth Mineralization Positive Regulation Of Mammary Gland Epithelial Cell Proliferation Positive Regulation Of Toll-like Receptor 9 Signaling Pathway Endoplasmic Reticulum Tubular Network Formation Alcohol Metabolic Process Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization
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