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CCT4
Gene Name
chaperonin containing TCP1, subunit 4 (delta)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Zona Pellucida Receptor Complex
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Chaperonin-containing T-complex
Microtubule
Melanosome
Cell Body
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
ATP Binding
Poly(A) RNA Binding
Unfolded Protein Binding
Biological Process
Protein Folding
Binding Of Sperm To Zona Pellucida
Cellular Protein Metabolic Process
'de Novo' Posttranslational Protein Folding
Toxin Transport
Pathways
Cargo trafficking to the periciliary membrane
Protein folding
Organelle biogenesis and maintenance
Prefoldin mediated transfer of substrate to CCT/TriC
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
Association of TriC/CCT with target proteins during biosynthesis
Chaperonin-mediated protein folding
Assembly of the primary cilium
BBSome-mediated cargo-targeting to cilium
Formation of tubulin folding intermediates by CCT/TriC
Folding of actin by CCT/TriC
Drugs
Diseases
GWAS
Protein-protein Interactions
10 interactors:
ACTA1
ACTA2
ACTB
CCNE1
CFAP52
PRPF40A
RFWD2
RPS6KA1
UBC
VRK2
Entrez ID
10575
HPRD ID
05506
Ensembl ID
ENSG00000115484
Uniprot IDs
B7Z2F4
P50991
PDB IDs
Enriched GO Terms of Interacting Partners
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Cell Cycle
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Regulation Of DNA-templated Transcription In Response To Stress
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Signal Transduction Involved In DNA Damage Checkpoint
Toll-like Receptor 9 Signaling Pathway
Signal Transduction Involved In Cell Cycle Checkpoint
Regulation Of Cell Cycle
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Mitotic G1 DNA Damage Checkpoint
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Positive Regulation Of Cell Cycle Arrest
DNA Damage Response, Signal Transduction By P53 Class Mediator
Toll-like Receptor 4 Signaling Pathway
Signal Transduction In Response To DNA Damage
Immune Response-regulating Signaling Pathway
Mitotic DNA Damage Checkpoint
Regulation Of Cell Cycle Arrest
Mitotic DNA Integrity Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle Process
Toll-like Receptor Signaling Pathway
Skeletal Muscle Fiber Adaptation
Positive Regulation Of Hepatic Stellate Cell Activation
Signal Transduction By P53 Class Mediator
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Pattern Recognition Receptor Signaling Pathway
Regulation Of Interleukin-1-mediated Signaling Pathway
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Innate Immune Response-activating Signal Transduction
Regulation Of Cell Cycle G1/S Phase Transition
Response To Stimulus
Activation Of Innate Immune Response
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Immune Response
Positive Regulation Of Cellular Protein Catabolic Process
DNA Damage Checkpoint
Movement Of Cell Or Subcellular Component
G1/S Transition Of Mitotic Cell Cycle
Tagcloud
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20s
assist
back
carry
cct5
chaperonin
chaperonins
cryo
crystallin
encapsulate
gammad
gradients
hetero
homo
hydrolyzed
individually
oligomeric
oligomers
organized
refolding
rings
sedimented
stain
sucrose
tcp
testes
tric
ubiquitous