RNASEH2A

Description		ribonuclease H2 subunit A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Ribonuclease H2 Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Nuclease Activity Endonuclease Activity RNA-DNA Hybrid Ribonuclease Activity RNA Nuclease Activity Protein Binding Hydrolase Activity Metal Ion Binding
	Biological Process	DNA Replication Mismatch Repair RNA Catabolic Process RNA Metabolic Process DNA Replication, Removal Of RNA Primer
Pathways
Drugs
Diseases		Aicardi-Goutieres Syndrome (AGS)
GWAS		Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
Interacting Genes		1 interacting genes: BRCA2
Entrez ID		10535
HPRD ID		06914
Ensembl ID		ENSG00000104889
Uniprot IDs		O75792
PDB IDs		3P56 3PUF 8YJZ
Enriched GO Terms of Interacting Partners?		Mitotic Recombination-dependent Replication Fork Processing BRCA2-MAGE-D1 Complex Lateral Element Nuclear Ubiquitin Ligase Complex Telomere Maintenance Via Recombination Regulation Of Mammary Gland Epithelial Cell Proliferation Inner Cell Mass Cell Proliferation Response To UV-C Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Histone H3 Acetyltransferase Activity DNA Repair Complex Histone H4 Acetyltransferase Activity Establishment Of Protein Localization To Telomere Centrosome Duplication Mitotic Recombination Oocyte Maturation Regulation Of DNA Damage Checkpoint Male Meiosis I Female Gonad Development Response To X-ray Hematopoietic Stem Cell Proliferation Histone Acetyltransferase Activity Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Gamma-tubulin Binding Replication Fork Processing Meiosis I DNA Damage Response, Signal Transduction By P53 Class Mediator Nucleotide-excision Repair Response To Gamma Radiation Male Meiotic Nuclear Division Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Senescence Meiosis I Cell Cycle Process Meiotic Nuclear Division Stem Cell Proliferation Cellular Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Cytokinesis Nuclear Division Telomere Maintenance Signal Transduction By P53 Class Mediator Secretory Granule Single-stranded DNA Binding Protease Binding Positive Regulation Of Mitotic Cell Cycle Telomere Organization Double-strand Break Repair Via Homologous Recombination Gonad Development Recombinational Repair Response To Ionizing Radiation
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