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HMGN4
Description
high mobility group nucleosomal binding domain 4
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Molecular Function
DNA Binding
Chromatin Binding
Protein Binding
Nucleosomal DNA Binding
Biological Process
Chromatin Organization
Pathways
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Brain morphology (MOSTest) (
32665545
)
Fish- and plant-related diet (
32066663
)
Gastroesophageal reflux disease (
34187846
)
General cognitive ability (
29844566
)
Hip circumference adjusted for BMI (
34021172
)
Lung cancer in ever smokers (
28604730
)
Refractive error (
32231278
)
Small cell lung carcinoma (
28604730
)
Subcortical volume (MOSTest) (
32665545
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
8 interacting genes:
CEBPA
EWSR1
HPF1
PARP1
SMO
TERF1
TERF2
TERF2IP
Entrez ID
10473
HPRD ID
17111
Ensembl ID
ENSG00000182952
Uniprot IDs
O00479
PDB IDs
Enriched GO Terms of Interacting Partners
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Negative Regulation Of Telomere Maintenance
Shelterin Complex
Nuclear Telomere Cap Complex
G-rich Strand Telomeric DNA Binding
Telomere Capping
Negative Regulation Of Chromosome Organization
Telomere Maintenance
Protein Localization To Chromosome
Regulation Of Telomere Maintenance
RNA-templated DNA Biosynthetic Process
Negative Regulation Of Telomeric D-loop Disassembly
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Negative Regulation Of DNA Recombination At Telomere
Telomere Organization
Telomeric DNA Binding
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of DNA Metabolic Process
Chromosome, Telomeric Region
Regulation Of Telomere Maintenance Via Telomere Lengthening
Regulation Of Chromosome Organization
Protein Localization To Organelle
Telomerase Activity
Protection From Non-homologous End Joining At Telomere
Positive Regulation Of Telomere Maintenance
Positive Regulation Of DNA Metabolic Process
Chromosome
Telomeric D-loop Disassembly
Double-stranded Telomeric DNA Binding
DNA Metabolic Process
DNA Biosynthetic Process
Macromolecule Biosynthetic Process
Chromosome Organization
Telomeric Loop Disassembly
Protein Localization To Chromosome, Telomeric Region
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Chromosome Organization
Nuclear Body
Nucleobase-containing Compound Biosynthetic Process
Telomere Maintenance In Response To DNA Damage
Protein Poly-ADP-ribosylation
Regulation Of DNA Recombination
Negative Regulation Of Telomere Maintenance Via Telomerase
Regulation Of DNA Metabolic Process
Telomere Maintenance Via Telomerase
Negative Regulation Of Phosphate Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
DNA Repair-dependent Chromatin Remodeling
Nucleic Acid Metabolic Process
Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of DNA Biosynthetic Process
Tagcloud
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