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TOMM40
Gene Name
translocase of outer mitochondrial membrane 40 homolog (yeast)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane Translocase Complex
Integral Component Of Membrane
Integral Component Of Mitochondrial Outer Membrane
Pore Complex
Extracellular Vesicular Exosome
Molecular Function
Protein Transmembrane Transporter Activity
Porin Activity
Biological Process
Protein Targeting To Mitochondrion
Ion Transport
Cellular Protein Metabolic Process
Protein Transmembrane Transport
Pathways
Mitochondrial protein import
Drugs
Diseases
GWAS
AB1-42 (
20932310
)
Age-related macular degeneration (
22694956
23326517
)
Alzheimer's disease (
22832961
18823527
19734902
19125160
20061627
)
Alzheimer's disease (age of onset) (
22005931
)
Alzheimer's disease (late onset) (
20885792
23565137
)
Alzheimer's disease biomarkers (
23562540
21123754
23419831
)
Brain imaging (
20100581
)
C-reactive protein (
22939635
)
Cardiovascular disease risk factors (
21943158
)
Cholesterol, total (
19060911
)
Cognitive decline (
22054870
23207651
)
HDL cholesterol (
21909109
19060911
)
LDL cholesterol (
19060911
)
Longevity (
21418511
)
Metabolic syndrome (
22399527
)
Quantitative traits (
19197348
)
Triglycerides (
19060911
)
Protein-protein Interactions
8 interactors:
HSP90AA1
HSPA4
MTX1
PARK2
SAMM50
TOMM20
TOMM22
TOMM7
Entrez ID
10452
HPRD ID
16274
Ensembl ID
ENSG00000130204
Uniprot IDs
O96008
PDB IDs
Enriched GO Terms of Interacting Partners
?
Protein Localization To Mitochondrion
Protein Targeting To Mitochondrion
Mitochondrial Transport
Protein Import Into Mitochondrial Outer Membrane
Protein Transmembrane Transport
Mitochondrion Organization
Protein Localization To Organelle
Establishment Of Protein Localization To Organelle
Intracellular Protein Transmembrane Transport
Protein Targeting
Cellular Protein Localization
Cytoplasmic Transport
Protein Import
Intracellular Protein Transport
Protein Localization
Mitochondrial Membrane Organization
Cellular Localization
Protein Transport
Establishment Of Protein Localization
Intracellular Transport
Organelle Organization
Establishment Of Localization In Cell
Establishment Of Protein Localization To Membrane
Protein Localization To Membrane
Transport
Transmembrane Transport
Chaperone-mediated Protein Complex Assembly
Response To Unfolded Protein
Cellular Protein Metabolic Process
Membrane Organization
Protein Metabolic Process
Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Mitochondrial Fusion
Positive Regulation Of Protein Linear Polyubiquitination
Dopamine Uptake Involved In Synaptic Transmission
Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Cellular Response To Dopamine
Regulation Of Reactive Oxygen Species Metabolic Process
Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Cellular Response To Manganese Ion
Protein K27-linked Ubiquitination
Protein K29-linked Ubiquitination
Negative Regulation Of Mitochondrial Fusion
Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Regulation Of Mitochondrial Fusion
Negative Regulation Of Glucokinase Activity
Neuron Cellular Homeostasis
Positive Regulation Of Oxidative Stress-induced Cell Death
Protein K6-linked Ubiquitination
Tagcloud
?
a2m
algorithm
allele
alzheimer
amplicons
apoe
apoj
bin1
biochip
clut
combinations
cr1
determina
e3
e4
epsilon2
epsilon4
exoc3l2
gab2
genotyping
immobilized
microchip
oligonucleotides
picalm
predis
rs11136000
sporadic
studying
tion