IFI30

Description		IFI30 lysosomal thiol reductase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Lysosome Cytosol Cell Junction Lysosomal Lumen
	Molecular Function	Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor
	Biological Process	Immune System Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Negative Regulation Of Fibroblast Proliferation Protein Stabilization
Pathways		MHC class II antigen presentation Interferon gamma signaling
Drugs
Diseases
GWAS		Mental health study participation (completed survey) ( 31263887) Multiple sclerosis ( 24076602 31604244) Serum alkaline phosphatase levels ( 33547301) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		3 interacting genes: KRTAP4-12 NOTCH2NLA TGM1
Entrez ID		10437
HPRD ID		05234
Ensembl ID		ENSG00000216490
Uniprot IDs		P13284
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Envelope Organization Peptide Cross-linking Positive Regulation Of Keratinocyte Proliferation Protein-glutamine Gamma-glutamyltransferase Activity Hair Cycle Notch Binding
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