MICU1

Name	mitochondrial calcium uptake 1
Structure
Interactors	4 interactors: APP OGT RIPK4 UBC
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane Mitochondrial Membrane Calcium Channel Complex Mitochondrial Crista Junction Uniplex Complex
	Molecular Function	Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Calcium Channel Inhibitor Activity Identical Protein Binding Metal Ion Binding Protein Heterodimerization Activity Calcium Ion Sensor Activity
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Mitochondrial Calcium Ion Transmembrane Transport Defense Response Calcium Import Into The Mitochondrion Protein Homooligomerization Mitochondrial Calcium Ion Homeostasis Positive Regulation Of Mitochondrial Calcium Ion Concentration Calcium Ion Import Cellular Response To Calcium Ion Cellular Response To Calcium Ion Starvation Regulation Of Cellular Hyperosmotic Salinity Response Positive Regulation Of Cristae Formation
Pathways	Mitochondrial calcium ion transport Processing of SMDT1
GWAS	Refractive error ( 32231278 )
Entrez ID	10367
HPRD ID	05471
Ensembl ID	ENSG00000107745
Uniprot IDs	A0A286YF11 Q9BPX6
PDB IDs	4NSC 4NSD 6K7Y 6LB7 6LB8 6LE5 6WDN 6WDO 6XJV 6XJX 6XQN 6XQO
GO Terms Enriched among Interactors ?	Amyloid-beta Complex Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Amylin Binding Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Toll Signaling Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Acetylcholine Receptor Activator Activity PTB Domain Binding Regulation Of Synapse Assembly Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Hemopoiesis Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Generation Of Precursor Metabolites And Energy Protein O-acetylglucosaminyltransferase Activity Positive Regulation Of Proteolysis Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Cell Junction Assembly Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Axon Choice Point Recognition Carbon Catabolite Regulation Of Transcription Regulation Of Synapse Organization