CDO1

Description		cysteine dioxygenase type 1
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GO Annotations	Cellular Component	Cytosol
	Molecular Function	Iron Ion Binding Ferrous Iron Binding Zinc Ion Binding Nickel Cation Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen Cysteine Dioxygenase Activity Metal Ion Binding Dioxygenase Activity
	Biological Process	Sulfur Amino Acid Biosynthetic Process Cysteine Metabolic Process Inflammatory Response Lactation L-cysteine Catabolic Process Response To Glucagon Taurine Biosynthetic Process Response To Amino Acid Response To Ethanol Response To Glucocorticoid Response To CAMP Response To Azide
Pathways		Degradation of cysteine and homocysteine
Drugs		Cysteine NADH
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Central corneal thickness ( 31798171 32528159) Circulating phylloquinone levels ( 25411281) Height ( 31562340) Intraocular pressure ( 29617998) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		1 interacting genes: CYP17A1
Entrez ID		1036
HPRD ID		06806
Ensembl ID		ENSG00000129596
Uniprot IDs		Q16878
PDB IDs		2IC1 6BGF 6BGM 6BPR 6BPS 6BPT 6BPU 6BPV 6BPW 6BPX 6CDH 6CDN 6E87 6N42 6N43 8VL9 8VLB
Enriched GO Terms of Interacting Partners?		Steroid 17-alpha-monooxygenase Activity Cortisol Biosynthetic Process Androgen Biosynthetic Process Glucocorticoid Biosynthetic Process Cortisol Metabolic Process Progesterone Metabolic Process Steroid Hydroxylase Activity Glucocorticoid Metabolic Process Sex Differentiation C21-steroid Hormone Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Oxygen Binding Androgen Metabolic Process Steroid Hormone Biosynthetic Process Ketone Biosynthetic Process Hormone Biosynthetic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Monooxygenase Activity Steroid Biosynthetic Process Ketone Metabolic Process Iron Ion Binding Heme Binding Olefinic Compound Metabolic Process Lyase Activity Hormone Metabolic Process Steroid Metabolic Process Alcohol Metabolic Process Neuronal Cell Body Axon Small Molecule Biosynthetic Process Lipid Biosynthetic Process Oxidoreductase Activity Regulation Of Hormone Levels
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