TLR6

Gene Name		toll-like receptor 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Phagocytic Vesicle Membrane Toll-like Receptor 2-Toll-like Receptor 6 Protein Complex
	Molecular Function	Receptor Activity Transmembrane Signaling Receptor Activity Diacyl Lipopeptide Binding Protein Heterodimerization Activity Lipopeptide Binding
	Biological Process	Toll-like Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Inflammatory Response Immune Response Signal Transduction Activation Of NF-kappaB-inducing Kinase Activity Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor 6 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway T-helper 1 Type Immune Response Detection Of Diacyl Bacterial Lipopeptide Defense Response To Bacterium Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JUN Kinase Activity Innate Immune Response Positive Regulation Of Interleukin-6 Biosynthetic Process Regulation Of Cytokine Secretion Cellular Response To Diacyl Bacterial Lipopeptide
Pathways		Toll Like Receptor 2 (TLR2) Cascade Toll Like Receptor TLR1:TLR2 Cascade Activated TLR4 signalling Toll-Like Receptors Cascades Toll Like Receptor 4 (TLR4) Cascade MyD88:Mal cascade initiated on plasma membrane Toll Like Receptor TLR6:TLR2 Cascade Innate Immune System
Drugs
Diseases
GWAS		Helicobacter pylori serologic status ( 23652523)
Protein-protein Interactions		3 interactors: BTK TLR2 TRAP1
Entrez ID		10333
HPRD ID		05656
Ensembl ID		ENSG00000174130
Uniprot IDs		B2R933 Q9Y2C9
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Molecule Of Fungal Origin Response To Fungus I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Regulation Of Reactive Oxygen Species Biosynthetic Process MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Cytokine Production Involved In Immune Response Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Chloramphenicol Transport Regulation Of B Cell Cytokine Production Induction By Symbiont Of Defense-related Host Nitric Oxide Production Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Innate Immune Response Cellular Response To Molecule Of Fungal Origin Cellular Response To Diacyl Bacterial Lipopeptide Cellular Response To Triacyl Bacterial Lipopeptide Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Innate Immune Response Response To Defense-related Host Nitric Oxide Production Positive Regulation Of Interleukin-18 Production Cell Surface Pattern Recognition Receptor Signaling Pathway Negative Regulation Of Cellular Respiration Immune Response-activating Cell Surface Receptor Signaling Pathway Detection Of Diacyl Bacterial Lipopeptide Detection Of Triacyl Bacterial Lipopeptide Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Antibiotic Transport Central Nervous System Myelin Formation Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Response To Peptidoglycan Response To Host Immune Response Inflammatory Response Detection Of Bacterial Lipoprotein Immune Response-regulating Signaling Pathway Leukocyte Activation Negative Regulation Of Interleukin-17 Production Cellular Response To Bacterial Lipopeptide Regulation Of Cytokine Production Positive Regulation Of Toll-like Receptor Signaling Pathway Histamine Secretion By Mast Cell Response To Peptidoglycan Regulation Of Cellular Respiration Microglial Cell Activation
Tagcloud ?		advance comprehensively doi genotyped haplotype household il18 il1b il4 influences kampala nod2 nominal online persistently publication resistors rstr rstrs slc6a3 snps suggestively tagging tb ticam2 tlr4 tollip tuberculin uganda