LILRB2

Gene Name		leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
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Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane
	Molecular Function	Receptor Activity Protein Binding Protein Phosphatase 1 Binding MHC Class Ib Protein Binding Inhibitory MHC Class I Receptor Activity MHC Class I Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Negative Regulation Of Antigen Processing And Presentation Positive Regulation Of T Cell Tolerance Induction Immune Response-inhibiting Cell Surface Receptor Signaling Pathway Fc Receptor Mediated Inhibitory Signaling Pathway Immune Response Cellular Defense Response Signal Transduction Cell Surface Receptor Signaling Pathway Cell-cell Signaling Positive Regulation Of Interleukin-6 Production Heterotypic Cell-cell Adhesion Positive Regulation Of T Cell Proliferation Negative Regulation Of T Cell Proliferation Positive Regulation Of Regulatory T Cell Differentiation Regulation Of Immune Response Negative Regulation Of Calcium Ion Transport Cellular Response To Lipopolysaccharide Regulation Of Dendritic Cell Differentiation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS		HDL cholesterol ( 20686565)
Protein-protein Interactions		7 interactors: FCGR1A HLA-A HLA-B HLA-C HLA-F HLA-G PTPN6
Entrez ID		10288
HPRD ID		11994
Ensembl ID		ENSG00000131042
Uniprot IDs		A2IXV5 A8MU67 C9JF29 Q8N423
PDB IDs		2DYP 2GW5 4LLA
Enriched GO Terms of Interacting Partners?		Interferon-gamma-mediated Signaling Pathway Cellular Response To Interferon-gamma Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Response To Interferon-gamma Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Response To Type I Interferon Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Positive Regulation Of T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of T Cell Mediated Cytotoxicity Regulation Of Adaptive Immune Response Positive Regulation Of Leukocyte Mediated Cytotoxicity Cytokine-mediated Signaling Pathway Positive Regulation Of Cell Killing Positive Regulation Of T Cell Mediated Immunity Regulation Of Leukocyte Mediated Cytotoxicity Antigen Processing And Presentation Of Peptide Antigen Cellular Response To Cytokine Stimulus Antigen Processing And Presentation Positive Regulation Of Immune Response Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Response To Cytokine Positive Regulation Of Adaptive Immune Response Innate Immune Response Regulation Of Immune Response Positive Regulation Of Immune System Process Immune Response Regulation Of Immune System Process Defense Response Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Endogenous Antigen Cellular Response To Organic Substance Immune System Process Response To Organic Substance Protection From Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Cell Surface Receptor Signaling Pathway Response To Stress Negative Regulation Of Immune System Process Regulation Of Dendritic Cell Differentiation Negative Regulation Of Immune Response Detection Of Bacterium Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Signal Transduction Detection Of Biotic Stimulus
Tagcloud ?		abilities acetylcholine adrenergic alpha7 alpha7nachr ars bindings characters deterioration drivers eph exact fcgamma fcgammariib immunoglobulin ltp neurotrophin nicotinic oligomeric ortholog p75ntr pirb presumed prion prpc rescuing spine summarizes synapse