DHRS9

Description		dehydrogenase/reductase 9
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Alcohol Dehydrogenase (NAD+) Activity All-trans-retinol Dehydrogenase (NAD+) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Racemase And Epimerase Activity Androsterone Dehydrogenase [NAD(P)+] Activity Testosterone Dehydrogenase (NAD+) Activity Androstan-3-alpha,17-beta-diol Dehydrogenase (NAD+) Activity
	Biological Process	Retinoic Acid Biosynthetic Process Lipid Metabolic Process Steroid Metabolic Process Androgen Metabolic Process Epithelial Cell Differentiation Progesterone Metabolic Process Retinol Metabolic Process 9-cis-retinoic Acid Biosynthetic Process
Pathways		The canonical retinoid cycle in rods (twilight vision) RA biosynthesis pathway
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Serum alkaline phosphatase levels ( 31666285 33547301)
Interacting Genes		1 interacting genes: STX8
Entrez ID		10170
HPRD ID		09916
Ensembl ID		ENSG00000073737
Uniprot IDs		Q9BPW9
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Chloride Channel Inhibitor Activity SNARE Binding SNARE Complex Syntaxin Binding Phagocytic Vesicle Response To Type II Interferon Organelle Membrane Fusion Early Endosome To Late Endosome Transport Vesicle Docking Cellular Response To Type II Interferon SNAP Receptor Activity Organelle Localization By Membrane Tethering Membrane Docking Membrane Fusion Recycling Endosome Regulation Of Protein Localization To Cell Periphery Regulation Of Protein Localization To Plasma Membrane Late Endosome Organelle Fusion Regulation Of Protein Localization To Membrane Vesicle Trans-Golgi Network Endomembrane System Endosomal Transport Vesicle Organization Early Endosome Ubiquitin Protein Ligase Binding
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