MBNL2

Description		muscleblind like splicing regulator 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	MRNA Processing RNA Splicing Regulation Of RNA Splicing
Pathways
Drugs
Diseases
GWAS		Alcoholism (alcohol dependence factor score) ( 21529783) Alcoholism (alcohol use disorder factor score) ( 21529783) Diastolic blood pressure ( 30224653) Energy expenditure (24h) ( 28476931) Lung function in heavy smokers (high FEV1 vs average FEV1) ( 26423011) Neurociticism ( 29500382) Obesity-related traits ( 23251661) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Platelet reactivity in response to clopidogrel treatment ( 32472697) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		5 interacting genes: MSI2 QKI RBPMS SNRPA TIAL1
Entrez ID		10150
HPRD ID		09543
Ensembl ID		ENSG00000139793
Uniprot IDs		A0A7P0T9I3 A0A994J506 A0A994J509 A2A3S3 Q5VZF2
PDB IDs		2E5S 2RPP
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding Cytoplasmic Stress Granule RNA Binding MRNA 3'-UTR Binding MRNA Binding Internal N(7)-methylguanine-containing RNA Reader Activity Regulation Of MRNA Splicing, Via Spliceosome Myofibroblast Contraction Regulation Of MRNA Processing Negative Regulation Of MiRNA Catabolic Process Spliceosomal SnRNP Complex RNA Processing Protein-RNA Adaptor Activity Regulation Of RNA Splicing Spliceosome-depend Formation Of Circular RNA MRNA CDS Binding MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of 3'-UTR-mediated MRNA Stabilization U1 SnRNA Binding U1 SnRNP Binding Microglia Differentiation Negative Regulation Of Macrophage Differentiation Transcription Coactivator Activity Vascular Associated Smooth Muscle Cell Differentiation Cytolytic Granule Positive Regulation Of MiRNA-mediated Gene Silencing Regulation Of MRNA Metabolic Process Intracellular MRNA Localization Pre-mRNA Intronic Binding RNA Splicing U1 SnRNP Regulation Of Translation Positive Regulation Of Myelination Pre-mRNA Binding MRNA Processing Positive Regulation Of Hippo Signaling Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Oligodendrocyte Differentiation Poly(U) RNA Binding Regulation Of Macrophage Differentiation SMAD Protein Signal Transduction Identical Protein Binding Regulation Of Post-transcriptional Gene Silencing Regulation Of MiRNA-mediated Gene Silencing Smooth Muscle Cell Differentiation Regulation Of Astrocyte Differentiation Stress Granule Assembly RNA Localization Regulation Of Cholesterol Biosynthetic Process
Tagcloud ?